Cargando…
Prediction of Burkholderia pseudomallei DsbA substrates identifies potential virulence factors and vaccine targets
Identification of bacterial virulence factors is critical for understanding disease pathogenesis, drug discovery and vaccine development. In this study we used two approaches to predict virulence factors of Burkholderia pseudomallei, the Gram-negative bacterium that causes melioidosis. B. pseudomall...
Autores principales: | Vezina, Ben, Petit, Guillaume A., Martin, Jennifer L., Halili, Maria A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678975/ https://www.ncbi.nlm.nih.gov/pubmed/33216758 http://dx.doi.org/10.1371/journal.pone.0241306 |
Ejemplares similares
-
Identification and characterization of two drug-like fragments that bind to the same cryptic binding pocket of Burkholderia pseudomallei DsbA
por: Petit, Guillaume A., et al.
Publicado: (2022) -
Comparative Sequence, Structure and Redox Analyses of Klebsiella pneumoniae DsbA Show That Anti-Virulence Target DsbA Enzymes Fall into Distinct Classes
por: Kurth, Fabian, et al.
Publicado: (2013) -
Virulence of the Melioidosis Pathogen Burkholderia pseudomallei Requires the Oxidoreductase Membrane Protein DsbB
por: McMahon, Róisín M., et al.
Publicado: (2018) -
Inhibition of Diverse DsbA Enzymes in Multi-DsbA Encoding Pathogens
por: Totsika, Makrina, et al.
Publicado: (2018) -
Oxidoreductase disulfide bond proteins DsbA and DsbB form an active redox pair in Chlamydia trachomatis, a bacterium with disulfide dependent infection and development
por: Christensen, Signe, et al.
Publicado: (2019)