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Custom-made artificial eyes using 3D printing for dogs: A preliminary study
Various incurable eye diseases in companion animals often result in phthisis bulbi and eye removal surgery. Currently, the evisceration method using silicone balls is useful in animals; however, it is not available to those with impaired cornea or severe ocular atrophy. Moreover, ocular implant and...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678976/ https://www.ncbi.nlm.nih.gov/pubmed/33216792 http://dx.doi.org/10.1371/journal.pone.0242274 |
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author | Park, So-Young An, Jeong-Hee Kwon, Hyun Choi, Seo-Young Lim, Ka-Young Kwak, Ho-Hyun Hussein, Kamal Hany Woo, Heung-Myong Park, Kyung-Mee |
author_facet | Park, So-Young An, Jeong-Hee Kwon, Hyun Choi, Seo-Young Lim, Ka-Young Kwak, Ho-Hyun Hussein, Kamal Hany Woo, Heung-Myong Park, Kyung-Mee |
author_sort | Park, So-Young |
collection | PubMed |
description | Various incurable eye diseases in companion animals often result in phthisis bulbi and eye removal surgery. Currently, the evisceration method using silicone balls is useful in animals; however, it is not available to those with impaired cornea or severe ocular atrophy. Moreover, ocular implant and prostheses are not widely used because of the diversity in animal size and eye shape, and high manufacturing cost. Here, we produced low-cost and customized artificial eyes, including implant and prosthesis, using computer-aided design and three-dimensional (3D) printing technique. For 3D modeling, the size of the artificial eyes was optimized using B-mode ultrasonography. The design was exported to STL files, and then printed using polycaprolactone (PCL) for prosthesis and mixture of PCL and hydroxyapatite (HA) for ocular implant. The 3D printed artificial eyes could be produced in less than one and half hour. The prosthesis was painted using oil colors and biocompatible resin. Two types of eye removal surgery, including evisceration and enucleation, were performed using two beagle dogs, as a preliminary study. After the surgery, the dogs were clinically evaluated for 6 months and then histopathological evaluation of the implant was done. Ocular implant was biocompatible and host tissue ingrowth was induced after in vivo application. The custom-made prosthesis was cosmetically excellent. Although long-term clinical follow-up might be required, the use of 3D printed-customized artificial eyes may be beneficial for animals that need personalized artificial eye surgery. |
format | Online Article Text |
id | pubmed-7678976 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-76789762020-12-02 Custom-made artificial eyes using 3D printing for dogs: A preliminary study Park, So-Young An, Jeong-Hee Kwon, Hyun Choi, Seo-Young Lim, Ka-Young Kwak, Ho-Hyun Hussein, Kamal Hany Woo, Heung-Myong Park, Kyung-Mee PLoS One Research Article Various incurable eye diseases in companion animals often result in phthisis bulbi and eye removal surgery. Currently, the evisceration method using silicone balls is useful in animals; however, it is not available to those with impaired cornea or severe ocular atrophy. Moreover, ocular implant and prostheses are not widely used because of the diversity in animal size and eye shape, and high manufacturing cost. Here, we produced low-cost and customized artificial eyes, including implant and prosthesis, using computer-aided design and three-dimensional (3D) printing technique. For 3D modeling, the size of the artificial eyes was optimized using B-mode ultrasonography. The design was exported to STL files, and then printed using polycaprolactone (PCL) for prosthesis and mixture of PCL and hydroxyapatite (HA) for ocular implant. The 3D printed artificial eyes could be produced in less than one and half hour. The prosthesis was painted using oil colors and biocompatible resin. Two types of eye removal surgery, including evisceration and enucleation, were performed using two beagle dogs, as a preliminary study. After the surgery, the dogs were clinically evaluated for 6 months and then histopathological evaluation of the implant was done. Ocular implant was biocompatible and host tissue ingrowth was induced after in vivo application. The custom-made prosthesis was cosmetically excellent. Although long-term clinical follow-up might be required, the use of 3D printed-customized artificial eyes may be beneficial for animals that need personalized artificial eye surgery. Public Library of Science 2020-11-20 /pmc/articles/PMC7678976/ /pubmed/33216792 http://dx.doi.org/10.1371/journal.pone.0242274 Text en © 2020 Park et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Park, So-Young An, Jeong-Hee Kwon, Hyun Choi, Seo-Young Lim, Ka-Young Kwak, Ho-Hyun Hussein, Kamal Hany Woo, Heung-Myong Park, Kyung-Mee Custom-made artificial eyes using 3D printing for dogs: A preliminary study |
title | Custom-made artificial eyes using 3D printing for dogs: A preliminary study |
title_full | Custom-made artificial eyes using 3D printing for dogs: A preliminary study |
title_fullStr | Custom-made artificial eyes using 3D printing for dogs: A preliminary study |
title_full_unstemmed | Custom-made artificial eyes using 3D printing for dogs: A preliminary study |
title_short | Custom-made artificial eyes using 3D printing for dogs: A preliminary study |
title_sort | custom-made artificial eyes using 3d printing for dogs: a preliminary study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678976/ https://www.ncbi.nlm.nih.gov/pubmed/33216792 http://dx.doi.org/10.1371/journal.pone.0242274 |
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