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COVID-19 in rheumatoid arthritis cases: an Iranian referral center experience
Coronavirus infections, known as COVID-19, can induce a fatal respiratory system infection and also affect other organs, such as the kidney and heart. The mortality rate has been estimated between 1 and 5% in previous reports; however, the mortality and morbidity can be higher in patients with the i...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679060/ https://www.ncbi.nlm.nih.gov/pubmed/33219453 http://dx.doi.org/10.1007/s10067-020-05464-y |
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author | Shadmanfar, Soraya Jonaidi-Jafari, Nematollah Jafari, Ramezan Rastgar-Moqaddam, Zeynab Saburi, Amin |
author_facet | Shadmanfar, Soraya Jonaidi-Jafari, Nematollah Jafari, Ramezan Rastgar-Moqaddam, Zeynab Saburi, Amin |
author_sort | Shadmanfar, Soraya |
collection | PubMed |
description | Coronavirus infections, known as COVID-19, can induce a fatal respiratory system infection and also affect other organs, such as the kidney and heart. The mortality rate has been estimated between 1 and 5% in previous reports; however, the mortality and morbidity can be higher in patients with the immune-deficiency condition. Rheumatoid arthritis (RA) is one of the most rheumatoid disorders, and it is important to report their clinical and paraclinical data when affected with COVID-19. Evidence about their laboratory and radiologic findings is limited. In this case series, 10 cases of chronic and approved rheumatoid arthritis (RA) affected by COVID-19 are presented. Only 40% had dry cough, but myalgia and weakness as the general first presentation of infections was reported in most cases (80%). Gastrointestinal symptoms, including nausea/vomiting, diarrhea, anorexia, and abdominal pain, were reported in 50% of individuals. In blood cell count, 30% of cases had thrombocytopenia, and ESR in all cases was positive. Abnormal CRP and elevated LDH were seen in 90% of cases. In HRCT assessment, all cases had an abnormal parenchymal pattern, and 90% of cases presented the usual pattern of COVID-19 (bilateral multifocal GGO/consolidation). Although it is a limited report, these findings are helpful for comparison of clinical and paraclinical cases in RA cases with normal cases. |
format | Online Article Text |
id | pubmed-7679060 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-76790602020-11-23 COVID-19 in rheumatoid arthritis cases: an Iranian referral center experience Shadmanfar, Soraya Jonaidi-Jafari, Nematollah Jafari, Ramezan Rastgar-Moqaddam, Zeynab Saburi, Amin Clin Rheumatol Case Based Review Coronavirus infections, known as COVID-19, can induce a fatal respiratory system infection and also affect other organs, such as the kidney and heart. The mortality rate has been estimated between 1 and 5% in previous reports; however, the mortality and morbidity can be higher in patients with the immune-deficiency condition. Rheumatoid arthritis (RA) is one of the most rheumatoid disorders, and it is important to report their clinical and paraclinical data when affected with COVID-19. Evidence about their laboratory and radiologic findings is limited. In this case series, 10 cases of chronic and approved rheumatoid arthritis (RA) affected by COVID-19 are presented. Only 40% had dry cough, but myalgia and weakness as the general first presentation of infections was reported in most cases (80%). Gastrointestinal symptoms, including nausea/vomiting, diarrhea, anorexia, and abdominal pain, were reported in 50% of individuals. In blood cell count, 30% of cases had thrombocytopenia, and ESR in all cases was positive. Abnormal CRP and elevated LDH were seen in 90% of cases. In HRCT assessment, all cases had an abnormal parenchymal pattern, and 90% of cases presented the usual pattern of COVID-19 (bilateral multifocal GGO/consolidation). Although it is a limited report, these findings are helpful for comparison of clinical and paraclinical cases in RA cases with normal cases. Springer International Publishing 2020-11-20 2021 /pmc/articles/PMC7679060/ /pubmed/33219453 http://dx.doi.org/10.1007/s10067-020-05464-y Text en © International League of Associations for Rheumatology (ILAR) 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Case Based Review Shadmanfar, Soraya Jonaidi-Jafari, Nematollah Jafari, Ramezan Rastgar-Moqaddam, Zeynab Saburi, Amin COVID-19 in rheumatoid arthritis cases: an Iranian referral center experience |
title | COVID-19 in rheumatoid arthritis cases: an Iranian referral center experience |
title_full | COVID-19 in rheumatoid arthritis cases: an Iranian referral center experience |
title_fullStr | COVID-19 in rheumatoid arthritis cases: an Iranian referral center experience |
title_full_unstemmed | COVID-19 in rheumatoid arthritis cases: an Iranian referral center experience |
title_short | COVID-19 in rheumatoid arthritis cases: an Iranian referral center experience |
title_sort | covid-19 in rheumatoid arthritis cases: an iranian referral center experience |
topic | Case Based Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679060/ https://www.ncbi.nlm.nih.gov/pubmed/33219453 http://dx.doi.org/10.1007/s10067-020-05464-y |
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