PPM1G restricts innate immune signaling mediated by STING and MAVS and is hijacked by KSHV for immune evasion

The adaptor proteins, STING and MAVS, are components of critical pathogen-sensing pathways that induce innate immunity. Phosphorylation of either adaptor results in activation of the type I interferon pathway. How this phosphorylation is regulated and how it is manipulated by pathogens remain largel...

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Detalles Bibliográficos
Autores principales: Yu, Kuai, Tian, Huabin, Deng, Hongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679160/
https://www.ncbi.nlm.nih.gov/pubmed/33219031
http://dx.doi.org/10.1126/sciadv.abd0276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679160/
https://www.ncbi.nlm.nih.gov/pubmed/33219031
http://dx.doi.org/10.1126/sciadv.abd0276

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