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PPM1G restricts innate immune signaling mediated by STING and MAVS and is hijacked by KSHV for immune evasion
The adaptor proteins, STING and MAVS, are components of critical pathogen-sensing pathways that induce innate immunity. Phosphorylation of either adaptor results in activation of the type I interferon pathway. How this phosphorylation is regulated and how it is manipulated by pathogens remain largel...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679160/ https://www.ncbi.nlm.nih.gov/pubmed/33219031 http://dx.doi.org/10.1126/sciadv.abd0276 |