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Ancestry-dependent gene expression correlates with reprogramming to pluripotency and multiple dynamic biological processes

Induced pluripotent stem cells (iPSCs) can be derived from differentiated cells, enabling the generation of personalized disease models by differentiating patient-derived iPSCs into disease-relevant cell lines. While genetic variability between different iPSC lines affects differentiation potential,...

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Detalles Bibliográficos
Autores principales: Bisogno, Laura S., Yang, Jun, Bennett, Brian D., Ward, James M., Mackey, Lantz C., Annab, Lois A., Bushel, Pierre R., Singhal, Sandeep, Schurman, Shepherd H., Byun, Jung S., Nápoles, Anna María, Pérez-Stable, Eliseo J., Fargo, David C., Gardner, Kevin, Archer, Trevor K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679169/
https://www.ncbi.nlm.nih.gov/pubmed/33219026
http://dx.doi.org/10.1126/sciadv.abc3851