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Ancestry-dependent gene expression correlates with reprogramming to pluripotency and multiple dynamic biological processes
Induced pluripotent stem cells (iPSCs) can be derived from differentiated cells, enabling the generation of personalized disease models by differentiating patient-derived iPSCs into disease-relevant cell lines. While genetic variability between different iPSC lines affects differentiation potential,...
Autores principales: | Bisogno, Laura S., Yang, Jun, Bennett, Brian D., Ward, James M., Mackey, Lantz C., Annab, Lois A., Bushel, Pierre R., Singhal, Sandeep, Schurman, Shepherd H., Byun, Jung S., Nápoles, Anna María, Pérez-Stable, Eliseo J., Fargo, David C., Gardner, Kevin, Archer, Trevor K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679169/ https://www.ncbi.nlm.nih.gov/pubmed/33219026 http://dx.doi.org/10.1126/sciadv.abc3851 |
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