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The association between body mass index class and coronavirus disease 2019 outcomes
BACKGROUND/OBJECTIVES: A growing body of data suggests that obesity influences coronavirus disease 2019 (COVID-19). Our study’s primary objective was to assess the association between body mass index (BMI) categories and critical forms of COVID-19. SUBJECTS/METHODS: Data on consecutive adult patient...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679236/ https://www.ncbi.nlm.nih.gov/pubmed/33221825 http://dx.doi.org/10.1038/s41366-020-00721-1 |
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author | Al-Salameh, Abdallah Lanoix, Jean-Philippe Bennis, Youssef Andrejak, Claire Brochot, Etienne Deschasse, Guillaume Dupont, Hervé Goeb, Vincent Jaureguy, Maité Lion, Sylvie Maizel, Julien Moyet, Julien Vaysse, Benoit Desailloud, Rachel Ganry, Olivier Schmit, Jean-Luc Lalau, Jean-Daniel |
author_facet | Al-Salameh, Abdallah Lanoix, Jean-Philippe Bennis, Youssef Andrejak, Claire Brochot, Etienne Deschasse, Guillaume Dupont, Hervé Goeb, Vincent Jaureguy, Maité Lion, Sylvie Maizel, Julien Moyet, Julien Vaysse, Benoit Desailloud, Rachel Ganry, Olivier Schmit, Jean-Luc Lalau, Jean-Daniel |
author_sort | Al-Salameh, Abdallah |
collection | PubMed |
description | BACKGROUND/OBJECTIVES: A growing body of data suggests that obesity influences coronavirus disease 2019 (COVID-19). Our study’s primary objective was to assess the association between body mass index (BMI) categories and critical forms of COVID-19. SUBJECTS/METHODS: Data on consecutive adult patients hospitalized with laboratory-confirmed COVID-19 at Amiens University Hospital (Amiens, France) were extracted retrospectively. The association between BMI categories and the composite primary endpoint (admission to the intensive care unit or death) was probed in a logistic regression analysis. RESULTS: In total, 433 patients were included, and BMI data were available for 329: 20 were underweight (6.1%), 95 have a normal weight (28.9%), 90 were overweight (27.4%), and 124 were obese (37.7%). The BMI category was associated with the primary endpoint in the fully adjusted model; the odds ratio (OR) [95% confidence interval (CI)] for overweight and obesity were respectively 1.58 [0.77–3.24] and 2.58 [1.28–5.31]. The ORs [95% CI] for ICU admission were similar for overweight (3.16 [1.29–8.06]) and obesity (3.05 [1.25–7.82]) in the fully adjusted model. The unadjusted ORs for death were similar in all BMI categories while obesity only was associated with higher risk after adjustment. CONCLUSIONS: Our results suggest that overweight (and not only obesity) is associated with ICU admission, but overweight is not associated with death. |
format | Online Article Text |
id | pubmed-7679236 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-76792362020-11-23 The association between body mass index class and coronavirus disease 2019 outcomes Al-Salameh, Abdallah Lanoix, Jean-Philippe Bennis, Youssef Andrejak, Claire Brochot, Etienne Deschasse, Guillaume Dupont, Hervé Goeb, Vincent Jaureguy, Maité Lion, Sylvie Maizel, Julien Moyet, Julien Vaysse, Benoit Desailloud, Rachel Ganry, Olivier Schmit, Jean-Luc Lalau, Jean-Daniel Int J Obes (Lond) Brief Communication BACKGROUND/OBJECTIVES: A growing body of data suggests that obesity influences coronavirus disease 2019 (COVID-19). Our study’s primary objective was to assess the association between body mass index (BMI) categories and critical forms of COVID-19. SUBJECTS/METHODS: Data on consecutive adult patients hospitalized with laboratory-confirmed COVID-19 at Amiens University Hospital (Amiens, France) were extracted retrospectively. The association between BMI categories and the composite primary endpoint (admission to the intensive care unit or death) was probed in a logistic regression analysis. RESULTS: In total, 433 patients were included, and BMI data were available for 329: 20 were underweight (6.1%), 95 have a normal weight (28.9%), 90 were overweight (27.4%), and 124 were obese (37.7%). The BMI category was associated with the primary endpoint in the fully adjusted model; the odds ratio (OR) [95% confidence interval (CI)] for overweight and obesity were respectively 1.58 [0.77–3.24] and 2.58 [1.28–5.31]. The ORs [95% CI] for ICU admission were similar for overweight (3.16 [1.29–8.06]) and obesity (3.05 [1.25–7.82]) in the fully adjusted model. The unadjusted ORs for death were similar in all BMI categories while obesity only was associated with higher risk after adjustment. CONCLUSIONS: Our results suggest that overweight (and not only obesity) is associated with ICU admission, but overweight is not associated with death. Nature Publishing Group UK 2020-11-21 2021 /pmc/articles/PMC7679236/ /pubmed/33221825 http://dx.doi.org/10.1038/s41366-020-00721-1 Text en © Springer Nature Limited 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Brief Communication Al-Salameh, Abdallah Lanoix, Jean-Philippe Bennis, Youssef Andrejak, Claire Brochot, Etienne Deschasse, Guillaume Dupont, Hervé Goeb, Vincent Jaureguy, Maité Lion, Sylvie Maizel, Julien Moyet, Julien Vaysse, Benoit Desailloud, Rachel Ganry, Olivier Schmit, Jean-Luc Lalau, Jean-Daniel The association between body mass index class and coronavirus disease 2019 outcomes |
title | The association between body mass index class and coronavirus disease 2019 outcomes |
title_full | The association between body mass index class and coronavirus disease 2019 outcomes |
title_fullStr | The association between body mass index class and coronavirus disease 2019 outcomes |
title_full_unstemmed | The association between body mass index class and coronavirus disease 2019 outcomes |
title_short | The association between body mass index class and coronavirus disease 2019 outcomes |
title_sort | association between body mass index class and coronavirus disease 2019 outcomes |
topic | Brief Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679236/ https://www.ncbi.nlm.nih.gov/pubmed/33221825 http://dx.doi.org/10.1038/s41366-020-00721-1 |
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