FUNDC1-dependent mitophagy induced by tPA protects neurons against cerebral ischemia-reperfusion injury

Autophagy of mitochondria, termed mitophagy, plays an important role in cerebral ischemia-reperfusion (IR) injury, but the mechanism is not yet clear. Tissue-type plasminogen activator (tPA) is the most important thrombolytic drug in the clinical treatment of ischemic stroke and has neuroprotective...

Descripción completa

Detalles Bibliográficos
Autores principales: Cai, Ying, Yang, Eryan, Yao, Xiuhua, Zhang, Xuebin, Wang, Qixue, Wang, Yunfei, Liu, Ji, Fan, Weijia, Yi, Kaikai, Kang, Chunsheng, Wu, Jialing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679257/
https://www.ncbi.nlm.nih.gov/pubmed/33212415
http://dx.doi.org/10.1016/j.redox.2020.101792

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679257/
https://www.ncbi.nlm.nih.gov/pubmed/33212415
http://dx.doi.org/10.1016/j.redox.2020.101792

Ejemplares similares