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Gamma-delta T cells stimulate IL-6 production by pancreatic stellate cells in pancreatic ductal adenocarcinoma

INTRODUCTION: The immunosuppressive tumor microenvironment promotes progression of pancreatic ductal adenocarcinoma (PDAC). γδ T cells infiltrate the pancreatic tumor stroma and support tumorigenesis through αβ T cell inhibition. Pancreatic stellate cell (PSC) activation contributes to pancreatic fi...

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Detalles Bibliográficos
Autores principales:	Seifert, Adrian M., List, Julian, Heiduk, Max, Decker, Rahel, von Renesse, Janusz, Meinecke, Ann-Christin, Aust, Daniela E., Welsch, Thilo, Weitz, Jürgen, Seifert, Lena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2020
Materias:	Original Article – Cancer Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679341/ https://www.ncbi.nlm.nih.gov/pubmed/32865617 http://dx.doi.org/10.1007/s00432-020-03367-8

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