Cargando…
Post-lockdown SARS-CoV-2 nucleic acid screening in nearly ten million residents of Wuhan, China
Stringent COVID-19 control measures were imposed in Wuhan between January 23 and April 8, 2020. Estimates of the prevalence of infection following the release of restrictions could inform post-lockdown pandemic management. Here, we describe a city-wide SARS-CoV-2 nucleic acid screening programme bet...
| Autores principales: | , , , , , , , , , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679396/ https://www.ncbi.nlm.nih.gov/pubmed/33219229 http://dx.doi.org/10.1038/s41467-020-19802-w |
| _version_ | 1783612333359104000 |
|---|---|
| author | Cao, Shiyi Gan, Yong Wang, Chao Bachmann, Max Wei, Shanbo Gong, Jie Huang, Yuchai Wang, Tiantian Li, Liqing Lu, Kai Jiang, Heng Gong, Yanhong Xu, Hongbin Shen, Xin Tian, Qingfeng Lv, Chuanzhu Song, Fujian Yin, Xiaoxv Lu, Zuxun |
| author_facet | Cao, Shiyi Gan, Yong Wang, Chao Bachmann, Max Wei, Shanbo Gong, Jie Huang, Yuchai Wang, Tiantian Li, Liqing Lu, Kai Jiang, Heng Gong, Yanhong Xu, Hongbin Shen, Xin Tian, Qingfeng Lv, Chuanzhu Song, Fujian Yin, Xiaoxv Lu, Zuxun |
| author_sort | Cao, Shiyi |
| collection | PubMed |
| description | Stringent COVID-19 control measures were imposed in Wuhan between January 23 and April 8, 2020. Estimates of the prevalence of infection following the release of restrictions could inform post-lockdown pandemic management. Here, we describe a city-wide SARS-CoV-2 nucleic acid screening programme between May 14 and June 1, 2020 in Wuhan. All city residents aged six years or older were eligible and 9,899,828 (92.9%) participated. No new symptomatic cases and 300 asymptomatic cases (detection rate 0.303/10,000, 95% CI 0.270–0.339/10,000) were identified. There were no positive tests amongst 1,174 close contacts of asymptomatic cases. 107 of 34,424 previously recovered COVID-19 patients tested positive again (re-positive rate 0.31%, 95% CI 0.423–0.574%). The prevalence of SARS-CoV-2 infection in Wuhan was therefore very low five to eight weeks after the end of lockdown. |
| format | Online Article Text |
| id | pubmed-7679396 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2020 |
| publisher | Nature Publishing Group UK |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-76793962020-11-24 Post-lockdown SARS-CoV-2 nucleic acid screening in nearly ten million residents of Wuhan, China Cao, Shiyi Gan, Yong Wang, Chao Bachmann, Max Wei, Shanbo Gong, Jie Huang, Yuchai Wang, Tiantian Li, Liqing Lu, Kai Jiang, Heng Gong, Yanhong Xu, Hongbin Shen, Xin Tian, Qingfeng Lv, Chuanzhu Song, Fujian Yin, Xiaoxv Lu, Zuxun Nat Commun Article Stringent COVID-19 control measures were imposed in Wuhan between January 23 and April 8, 2020. Estimates of the prevalence of infection following the release of restrictions could inform post-lockdown pandemic management. Here, we describe a city-wide SARS-CoV-2 nucleic acid screening programme between May 14 and June 1, 2020 in Wuhan. All city residents aged six years or older were eligible and 9,899,828 (92.9%) participated. No new symptomatic cases and 300 asymptomatic cases (detection rate 0.303/10,000, 95% CI 0.270–0.339/10,000) were identified. There were no positive tests amongst 1,174 close contacts of asymptomatic cases. 107 of 34,424 previously recovered COVID-19 patients tested positive again (re-positive rate 0.31%, 95% CI 0.423–0.574%). The prevalence of SARS-CoV-2 infection in Wuhan was therefore very low five to eight weeks after the end of lockdown. Nature Publishing Group UK 2020-11-20 /pmc/articles/PMC7679396/ /pubmed/33219229 http://dx.doi.org/10.1038/s41467-020-19802-w Text en © The Author(s) 2020, corrected publication 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
| spellingShingle | Article Cao, Shiyi Gan, Yong Wang, Chao Bachmann, Max Wei, Shanbo Gong, Jie Huang, Yuchai Wang, Tiantian Li, Liqing Lu, Kai Jiang, Heng Gong, Yanhong Xu, Hongbin Shen, Xin Tian, Qingfeng Lv, Chuanzhu Song, Fujian Yin, Xiaoxv Lu, Zuxun Post-lockdown SARS-CoV-2 nucleic acid screening in nearly ten million residents of Wuhan, China |
| title | Post-lockdown SARS-CoV-2 nucleic acid screening in nearly ten million residents of Wuhan, China |
| title_full | Post-lockdown SARS-CoV-2 nucleic acid screening in nearly ten million residents of Wuhan, China |
| title_fullStr | Post-lockdown SARS-CoV-2 nucleic acid screening in nearly ten million residents of Wuhan, China |
| title_full_unstemmed | Post-lockdown SARS-CoV-2 nucleic acid screening in nearly ten million residents of Wuhan, China |
| title_short | Post-lockdown SARS-CoV-2 nucleic acid screening in nearly ten million residents of Wuhan, China |
| title_sort | post-lockdown sars-cov-2 nucleic acid screening in nearly ten million residents of wuhan, china |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679396/ https://www.ncbi.nlm.nih.gov/pubmed/33219229 http://dx.doi.org/10.1038/s41467-020-19802-w |
| work_keys_str_mv | AT caoshiyi postlockdownsarscov2nucleicacidscreeninginnearlytenmillionresidentsofwuhanchina AT ganyong postlockdownsarscov2nucleicacidscreeninginnearlytenmillionresidentsofwuhanchina AT wangchao postlockdownsarscov2nucleicacidscreeninginnearlytenmillionresidentsofwuhanchina AT bachmannmax postlockdownsarscov2nucleicacidscreeninginnearlytenmillionresidentsofwuhanchina AT weishanbo postlockdownsarscov2nucleicacidscreeninginnearlytenmillionresidentsofwuhanchina AT gongjie postlockdownsarscov2nucleicacidscreeninginnearlytenmillionresidentsofwuhanchina AT huangyuchai postlockdownsarscov2nucleicacidscreeninginnearlytenmillionresidentsofwuhanchina AT wangtiantian postlockdownsarscov2nucleicacidscreeninginnearlytenmillionresidentsofwuhanchina AT liliqing postlockdownsarscov2nucleicacidscreeninginnearlytenmillionresidentsofwuhanchina AT lukai postlockdownsarscov2nucleicacidscreeninginnearlytenmillionresidentsofwuhanchina AT jiangheng postlockdownsarscov2nucleicacidscreeninginnearlytenmillionresidentsofwuhanchina AT gongyanhong postlockdownsarscov2nucleicacidscreeninginnearlytenmillionresidentsofwuhanchina AT xuhongbin postlockdownsarscov2nucleicacidscreeninginnearlytenmillionresidentsofwuhanchina AT shenxin postlockdownsarscov2nucleicacidscreeninginnearlytenmillionresidentsofwuhanchina AT tianqingfeng postlockdownsarscov2nucleicacidscreeninginnearlytenmillionresidentsofwuhanchina AT lvchuanzhu postlockdownsarscov2nucleicacidscreeninginnearlytenmillionresidentsofwuhanchina AT songfujian postlockdownsarscov2nucleicacidscreeninginnearlytenmillionresidentsofwuhanchina AT yinxiaoxv postlockdownsarscov2nucleicacidscreeninginnearlytenmillionresidentsofwuhanchina AT luzuxun postlockdownsarscov2nucleicacidscreeninginnearlytenmillionresidentsofwuhanchina |