Pac-Man like DNA cut-and-paste tool allows larger gene edits

The CRISPR-Cas toolbox allows genetic manipulation of cultured cells, plants and animals on the basis of simpler RNA-guided DNA recognition. It has provided breakthrough scientific opportunities to engineer desirable traits, cure genetic diseases and enable point-of-care diagnostics. A recent study...

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Detalles Bibliográficos
Autor principal: Akhtar, Anam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Research Highlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679406/
https://www.ncbi.nlm.nih.gov/pubmed/33219320
http://dx.doi.org/10.1038/s42003-020-01446-7
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author Akhtar, Anam
author_facet Akhtar, Anam
author_sort Akhtar, Anam
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description The CRISPR-Cas toolbox allows genetic manipulation of cultured cells, plants and animals on the basis of simpler RNA-guided DNA recognition. It has provided breakthrough scientific opportunities to engineer desirable traits, cure genetic diseases and enable point-of-care diagnostics. A recent study by Joseph Bondy-Denomy and colleagues further equips this toolbox to cut larger chunks of DNA from a cell’s genome.
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spelling pubmed-76794062020-11-24 Pac-Man like DNA cut-and-paste tool allows larger gene edits Akhtar, Anam Commun Biol Research Highlight The CRISPR-Cas toolbox allows genetic manipulation of cultured cells, plants and animals on the basis of simpler RNA-guided DNA recognition. It has provided breakthrough scientific opportunities to engineer desirable traits, cure genetic diseases and enable point-of-care diagnostics. A recent study by Joseph Bondy-Denomy and colleagues further equips this toolbox to cut larger chunks of DNA from a cell’s genome. Nature Publishing Group UK 2020-11-20 /pmc/articles/PMC7679406/ /pubmed/33219320 http://dx.doi.org/10.1038/s42003-020-01446-7 Text en © Springer Nature Limited 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Highlight
Akhtar, Anam
Pac-Man like DNA cut-and-paste tool allows larger gene edits
title Pac-Man like DNA cut-and-paste tool allows larger gene edits
title_full Pac-Man like DNA cut-and-paste tool allows larger gene edits
title_fullStr Pac-Man like DNA cut-and-paste tool allows larger gene edits
title_full_unstemmed Pac-Man like DNA cut-and-paste tool allows larger gene edits
title_short Pac-Man like DNA cut-and-paste tool allows larger gene edits
title_sort pac-man like dna cut-and-paste tool allows larger gene edits
topic Research Highlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679406/
https://www.ncbi.nlm.nih.gov/pubmed/33219320
http://dx.doi.org/10.1038/s42003-020-01446-7
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