Optimization of post-insertion method to conjugate Doxil with anti-CD133 monoclonal antibodies: Investigating the specific binding and cytotoxicity to colorectal cancer cells in vitro

In this paper, Doxil coupled with anti-CD133 monoclonal antibodies made by either routine or optimized post-insertion technique, were compared with respect to their size, drug leakage, release pattern and the number of antibodies conjugated per single liposome. The results demonstrated that the numb...

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Detalles Bibliográficos
Autores principales: Dadashi Noshahr, Karim, Shamsi, Fahimeh, Valtchev, Peter, Kokhaei, Parviz, Hemati, Maral, Reza Akbari Eidgahi, Mohammad, Khaleghian, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679470/
https://www.ncbi.nlm.nih.gov/pubmed/33250646
http://dx.doi.org/10.1016/j.jsps.2020.09.003

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