Cargando…

Techniques assisting peptide vaccine and peptidomimetic design. Sidechain exposure in the SARS-CoV-2 spike glycoprotein

The aim of the present study is to discuss the design of peptide vaccines and peptidomimetics against SARS-COV-2, to develop and apply a method of protein structure analysis that is particularly appropriate to applying and discussing such design, and also to use that method to summarize some importa...

Descripción completa

Detalles Bibliográficos
Autor principal:	Robson, B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679524/ https://www.ncbi.nlm.nih.gov/pubmed/33276271 http://dx.doi.org/10.1016/j.compbiomed.2020.104124

Ejemplares similares

Structure-Based Design of Novel Peptidomimetics Targeting the SARS-CoV-2 Spike Protein
por: Alagumuthu, Manikandan, et al.
Publicado: (2020)

SwissSidechain: a molecular and structural database of non-natural sidechains
por: Gfeller, David, et al.
Publicado: (2013)

Ribosomal Incorporation of Aromatic Oligoamides as Peptide Sidechain Appendages
por: Tsiamantas, Christos, et al.
Publicado: (2020)

Peptides and Peptidomimetics for Antimicrobial Drug Design
por: Mojsoska, Biljana, et al.
Publicado: (2015)

Immuno-informatics design of a multimeric epitope peptide based vaccine targeting SARS-CoV-2 spike glycoprotein
por: Chukwudozie, Onyeka S., et al.
Publicado: (2021)

Stapled ACE2 peptidomimetics designed to target the SARS‐CoV‐2 spike protein do not prevent virus internalization
por: Morgan, Danielle C., et al.
Publicado: (2021)

The SARS-CoV-2 Spike Glycoprotein Biosynthesis, Structure, Function, and Antigenicity: Implications for the Design of Spike-Based Vaccine Immunogens
por: Duan, Liangwei, et al.
Publicado: (2020)

Immunoinformatics characterization of SARS-CoV-2 spike glycoprotein for prioritization of epitope based multivalent peptide vaccine
por: Ismail, Saba, et al.
Publicado: (2020)

Suppression of SARS-CoV entry by peptides corresponding to heptad regions on spike glycoprotein
por: Yuan, Kehu, et al.
Publicado: (2004)

Immunoinformatics Study: Multi-Epitope Based Vaccine Design from SARS-CoV-2 Spike Glycoprotein
por: Umitaibatin, Ramadhita, et al.
Publicado: (2023)

Novel Polymyxin-Inspired Peptidomimetics Targeting the SARS-CoV-2 Spike:hACE2 Interface
por: Bugatti, Kelly, et al.
Publicado: (2023)

Structural Diversity and Function of Xyloglucan Sidechain Substituents
por: Schultink, Alex, et al.
Publicado: (2014)

Bioinformatics and Biosimulations as Toolbox for Peptides and Peptidomimetics Design: Where Are We?
por: D’Annessa, Ilda, et al.
Publicado: (2020)

Translocating Peptides of Biomedical Interest Obtained from the Spike (S) Glycoprotein of the SARS-CoV-2
por: Henao, Maria C., et al.
Publicado: (2022)

Evidence supporting the use of peptides and peptidomimetics as potential SARS-CoV-2 (COVID-19) therapeutics
por: VanPatten, Sonya, et al.
Publicado: (2020)

Macrocyclization strategies for cyclic peptides and peptidomimetics
por: Bechtler, Clément, et al.
Publicado: (2021)

Exploiting Knowledge on Structure–Activity Relationships for Designing Peptidomimetics of Endogenous Peptides
por: Perez, Juan J.
Publicado: (2021)

Optimized Pseudotyping Conditions for the SARS-COV-2 Spike Glycoprotein
por: Johnson, Marc C., et al.
Publicado: (2020)

Expression, Glycosylation, and Modification of the Spike (S) Glycoprotein of SARS CoV
por: Shen, Shuo, et al.
Publicado: (2007)

Controlling the SARS-CoV-2 Spike Glycoprotein Conformation
por: Henderson, Rory, et al.
Publicado: (2020)

Controlling the SARS-CoV-2 spike glycoprotein conformation
por: Henderson, Rory, et al.
Publicado: (2020)

Heme binding to the SARS-CoV-2 spike glycoprotein
por: Freeman, Samuel L., et al.
Publicado: (2023)

Bioinformatics studies on a function of the SARS-CoV-2 spike glycoprotein as the binding of host sialic acid glycans
por: Robson, B.
Publicado: (2020)

SARS-CoV-2 Vaccines Based on the Spike Glycoprotein and Implications of New Viral Variants
por: Martínez-Flores, Daniel, et al.
Publicado: (2021)

Computers and viral diseases. Preliminary bioinformatics studies on the design of a synthetic vaccine and a preventative peptidomimetic antagonist against the SARS-CoV-2 (2019-nCoV, COVID-19) coronavirus
por: Robson, B.
Publicado: (2020)

Glycoprotein molecular dynamics analysis: SARS-CoV-2 spike glycoprotein case study
por: Coutinho, João Victor Paccini, et al.
Publicado: (2022)

Peptide modelling and screening against human ACE2 and spike glycoprotein RBD of SARS-CoV-2
por: Rathod, Shravan B., et al.
Publicado: (2020)

The Conformational Flexibility of an Internal Fusion Peptide from Sars-Cov Spike Glycoprotein is Modulated by Lipid Membrane Composition
por: Basso, Luis G.M., et al.
Publicado: (2014)

Structure-based design, synthesis, and biological evaluation of peptidomimetic SARS-CoV 3CLpro inhibitors
por: Ghosh, Arun K., et al.
Publicado: (2007)

Rational Design of SARS-CoV-2 Spike Glycoproteins To Increase Immunogenicity By T Cell Epitope Engineering
por: Ong, Edison, et al.
Publicado: (2020)

Computational design of SARS-CoV-2 spike glycoproteins to increase immunogenicity by T cell epitope engineering
por: Ong, Edison, et al.
Publicado: (2020)

Screening, simulation, and optimization design of small molecule inhibitors of the SARS-CoV-2 spike glycoprotein
por: Sun, Chuancai, et al.
Publicado: (2021)

Implications for SARS-CoV-2 Vaccine Design: Fusion of Spike Glycoprotein Transmembrane Domain to Receptor-Binding Domain Induces Trimerization
por: Azad, Taha, et al.
Publicado: (2020)

Antibody-mediated disruption of the SARS-CoV-2 spike glycoprotein
por: Wrobel, Antoni G., et al.
Publicado: (2020)

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein
por: Walls, Alexandra C., et al.
Publicado: (2020)

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein
por: Walls, Alexandra C., et al.
Publicado: (2020)

Exploring dynamics and network analysis of spike glycoprotein of SARS-COV-2
por: Ghorbani, Mahdi, et al.
Publicado: (2021)

Evolutionary Dynamics of Indels in SARS-CoV-2 Spike Glycoprotein
por: Rao, R Shyama Prasad, et al.
Publicado: (2021)

Uncovering cryptic pockets in the SARS-CoV-2 spike glycoprotein
por: Zuzic, Lorena, et al.
Publicado: (2022)

Structural dynamics in the evolution of SARS-CoV-2 spike glycoprotein
por: Calvaresi, Valeria, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_j4m1b066rdqrggt6md3msjlgli