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Thermal inactivation of SARS COVID-2 virus: Are steam inhalations a potential treatment?
BACKGROUND: The emergence of SARS-CoV-2 pandemic has upset health systems around the world and caused immeasurable losses and costs. Until a vaccine will become available, the recommended prevention measures remain physical distancing and enhanced hygiene. METHODS AND FINDINGS: The proteic structure...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680040/ https://www.ncbi.nlm.nih.gov/pubmed/33232690 http://dx.doi.org/10.1016/j.lfs.2020.118801 |
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author | la Marca, Giancarlo Barp, Jacopo Frenos, Stefano Mugelli, Alessandro Galli, Luisa Calistri, Elisa Biasucci, Giacomo De Masi, Salvatore Guerrini, Renzo |
author_facet | la Marca, Giancarlo Barp, Jacopo Frenos, Stefano Mugelli, Alessandro Galli, Luisa Calistri, Elisa Biasucci, Giacomo De Masi, Salvatore Guerrini, Renzo |
author_sort | la Marca, Giancarlo |
collection | PubMed |
description | BACKGROUND: The emergence of SARS-CoV-2 pandemic has upset health systems around the world and caused immeasurable losses and costs. Until a vaccine will become available, the recommended prevention measures remain physical distancing and enhanced hygiene. METHODS AND FINDINGS: The proteic structure external to the virus is the main target that may eventually lead to reduce or block its replication in the upper airways. We developed a protocol based of repeated steam inhalation cycles aimed at reducing the risk of progression to full blown infection if performed soon after contagion. The protocol has been used in a single-center open label trial on ten infected asymptomatic or pauci-symptomatic health care professionals. CONCLUSIONS: The promising results we obtained with this easily accessible, non-invasive and inexpensive procedure should prompt controlled trials. |
format | Online Article Text |
id | pubmed-7680040 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-76800402020-11-23 Thermal inactivation of SARS COVID-2 virus: Are steam inhalations a potential treatment? la Marca, Giancarlo Barp, Jacopo Frenos, Stefano Mugelli, Alessandro Galli, Luisa Calistri, Elisa Biasucci, Giacomo De Masi, Salvatore Guerrini, Renzo Life Sci Article BACKGROUND: The emergence of SARS-CoV-2 pandemic has upset health systems around the world and caused immeasurable losses and costs. Until a vaccine will become available, the recommended prevention measures remain physical distancing and enhanced hygiene. METHODS AND FINDINGS: The proteic structure external to the virus is the main target that may eventually lead to reduce or block its replication in the upper airways. We developed a protocol based of repeated steam inhalation cycles aimed at reducing the risk of progression to full blown infection if performed soon after contagion. The protocol has been used in a single-center open label trial on ten infected asymptomatic or pauci-symptomatic health care professionals. CONCLUSIONS: The promising results we obtained with this easily accessible, non-invasive and inexpensive procedure should prompt controlled trials. Elsevier Inc. 2021-01-15 2020-11-21 /pmc/articles/PMC7680040/ /pubmed/33232690 http://dx.doi.org/10.1016/j.lfs.2020.118801 Text en © 2020 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article la Marca, Giancarlo Barp, Jacopo Frenos, Stefano Mugelli, Alessandro Galli, Luisa Calistri, Elisa Biasucci, Giacomo De Masi, Salvatore Guerrini, Renzo Thermal inactivation of SARS COVID-2 virus: Are steam inhalations a potential treatment? |
title | Thermal inactivation of SARS COVID-2 virus: Are steam inhalations a potential treatment? |
title_full | Thermal inactivation of SARS COVID-2 virus: Are steam inhalations a potential treatment? |
title_fullStr | Thermal inactivation of SARS COVID-2 virus: Are steam inhalations a potential treatment? |
title_full_unstemmed | Thermal inactivation of SARS COVID-2 virus: Are steam inhalations a potential treatment? |
title_short | Thermal inactivation of SARS COVID-2 virus: Are steam inhalations a potential treatment? |
title_sort | thermal inactivation of sars covid-2 virus: are steam inhalations a potential treatment? |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680040/ https://www.ncbi.nlm.nih.gov/pubmed/33232690 http://dx.doi.org/10.1016/j.lfs.2020.118801 |
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