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Thermal inactivation of SARS COVID-2 virus: Are steam inhalations a potential treatment?

BACKGROUND: The emergence of SARS-CoV-2 pandemic has upset health systems around the world and caused immeasurable losses and costs. Until a vaccine will become available, the recommended prevention measures remain physical distancing and enhanced hygiene. METHODS AND FINDINGS: The proteic structure...

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Autores principales: la Marca, Giancarlo, Barp, Jacopo, Frenos, Stefano, Mugelli, Alessandro, Galli, Luisa, Calistri, Elisa, Biasucci, Giacomo, De Masi, Salvatore, Guerrini, Renzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680040/
https://www.ncbi.nlm.nih.gov/pubmed/33232690
http://dx.doi.org/10.1016/j.lfs.2020.118801
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author la Marca, Giancarlo
Barp, Jacopo
Frenos, Stefano
Mugelli, Alessandro
Galli, Luisa
Calistri, Elisa
Biasucci, Giacomo
De Masi, Salvatore
Guerrini, Renzo
author_facet la Marca, Giancarlo
Barp, Jacopo
Frenos, Stefano
Mugelli, Alessandro
Galli, Luisa
Calistri, Elisa
Biasucci, Giacomo
De Masi, Salvatore
Guerrini, Renzo
author_sort la Marca, Giancarlo
collection PubMed
description BACKGROUND: The emergence of SARS-CoV-2 pandemic has upset health systems around the world and caused immeasurable losses and costs. Until a vaccine will become available, the recommended prevention measures remain physical distancing and enhanced hygiene. METHODS AND FINDINGS: The proteic structure external to the virus is the main target that may eventually lead to reduce or block its replication in the upper airways. We developed a protocol based of repeated steam inhalation cycles aimed at reducing the risk of progression to full blown infection if performed soon after contagion. The protocol has been used in a single-center open label trial on ten infected asymptomatic or pauci-symptomatic health care professionals. CONCLUSIONS: The promising results we obtained with this easily accessible, non-invasive and inexpensive procedure should prompt controlled trials.
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spelling pubmed-76800402020-11-23 Thermal inactivation of SARS COVID-2 virus: Are steam inhalations a potential treatment? la Marca, Giancarlo Barp, Jacopo Frenos, Stefano Mugelli, Alessandro Galli, Luisa Calistri, Elisa Biasucci, Giacomo De Masi, Salvatore Guerrini, Renzo Life Sci Article BACKGROUND: The emergence of SARS-CoV-2 pandemic has upset health systems around the world and caused immeasurable losses and costs. Until a vaccine will become available, the recommended prevention measures remain physical distancing and enhanced hygiene. METHODS AND FINDINGS: The proteic structure external to the virus is the main target that may eventually lead to reduce or block its replication in the upper airways. We developed a protocol based of repeated steam inhalation cycles aimed at reducing the risk of progression to full blown infection if performed soon after contagion. The protocol has been used in a single-center open label trial on ten infected asymptomatic or pauci-symptomatic health care professionals. CONCLUSIONS: The promising results we obtained with this easily accessible, non-invasive and inexpensive procedure should prompt controlled trials. Elsevier Inc. 2021-01-15 2020-11-21 /pmc/articles/PMC7680040/ /pubmed/33232690 http://dx.doi.org/10.1016/j.lfs.2020.118801 Text en © 2020 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
la Marca, Giancarlo
Barp, Jacopo
Frenos, Stefano
Mugelli, Alessandro
Galli, Luisa
Calistri, Elisa
Biasucci, Giacomo
De Masi, Salvatore
Guerrini, Renzo
Thermal inactivation of SARS COVID-2 virus: Are steam inhalations a potential treatment?
title Thermal inactivation of SARS COVID-2 virus: Are steam inhalations a potential treatment?
title_full Thermal inactivation of SARS COVID-2 virus: Are steam inhalations a potential treatment?
title_fullStr Thermal inactivation of SARS COVID-2 virus: Are steam inhalations a potential treatment?
title_full_unstemmed Thermal inactivation of SARS COVID-2 virus: Are steam inhalations a potential treatment?
title_short Thermal inactivation of SARS COVID-2 virus: Are steam inhalations a potential treatment?
title_sort thermal inactivation of sars covid-2 virus: are steam inhalations a potential treatment?
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680040/
https://www.ncbi.nlm.nih.gov/pubmed/33232690
http://dx.doi.org/10.1016/j.lfs.2020.118801
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