Cholesteryl ester levels are elevated in the caudate and putamen of Huntington’s disease patients

Huntington’s disease (HD) is an autosomal dominant neurodegenerative illness caused by a mutation in the huntingtin gene (HTT) and subsequent protein (mhtt), to which the brain shows a region-specific vulnerability. Disturbances in neural cholesterol metabolism are established in HD human, murine an...

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Detalles Bibliográficos
Autores principales: Phillips, Gabrielle R., Hancock, Sarah E., Brown, Simon H. J., Jenner, Andrew M., Kreilaus, Fabian, Newell, Kelly A., Mitchell, Todd W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680097/
https://www.ncbi.nlm.nih.gov/pubmed/33219259
http://dx.doi.org/10.1038/s41598-020-76973-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680097/
https://www.ncbi.nlm.nih.gov/pubmed/33219259
http://dx.doi.org/10.1038/s41598-020-76973-8

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