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Dynamically encoded reactivity of Ras enzymes: opening new frontiers for drug discovery
Decoding molecular flexibility in order to understand and predict biological processes—applying the principles of dynamic-structure-activity relationships (DSAR)—becomes a necessity when attempting to design selective and specific inhibitors of a protein that has overlapping interaction surfaces wit...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680338/ https://www.ncbi.nlm.nih.gov/pubmed/32815102 http://dx.doi.org/10.1007/s10555-020-09917-3 |