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Her2 promotes early dissemination of breast cancer by suppressing the p38 pathway through Skp2-mediated proteasomal degradation of Tpl2

While mechanisms for metastasis were extensively studied in cancer cells from patients with detectable tumors, pathways underlying metastatic dissemination from early lesions before primary tumors appear are poorly understood. Her2 promotes breast cancer early dissemination by suppressing p38, but h...

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Detalles Bibliográficos
Autores principales: Wang, Guanwen, Wang, Juan, Chang, Antao, Cheng, Dongmei, Huang, Shan, Wu, Dan, Sirkisoon, Sherona, Yang, Shuang, Lin, Hui-Kuan, Lo, Hui-Wen, Xiang, Rong, Sun, Peiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680376/
https://www.ncbi.nlm.nih.gov/pubmed/32989258
http://dx.doi.org/10.1038/s41388-020-01481-y