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Four sesquiterpene glycosides from loquat (Eriobotrya japonica) leaf ameliorates palmitic acid-induced insulin resistance and lipid accumulation in HepG2 Cells via AMPK signaling pathway

Insulin resistance (IR), caused by impaired insulin signal and decreased insulin sensitivity, is generally responsible for the pathophysiology of type 2 diabetes mellitus (T2DM). Sesquiterpene glycosides (SGs), the exclusive natural products from loquat leaf, have been regarded as potential lead com...

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Detalles Bibliográficos
Autores principales:	Li, Jiawei, Ding, Xiaoqin, Jian, Tunyu, Lü, Han, Zhao, Lei, Li, Jing, Liu, Yan, Ren, Bingru, Chen, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2020
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680621/ https://www.ncbi.nlm.nih.gov/pubmed/33240683 http://dx.doi.org/10.7717/peerj.10413

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