QbD-Based Investigation of Dermal Semisolid in situ Film-Forming Systems for Local Anaesthesia

PURPOSE: The aim of our research work was to develop dermally applicable, lidocaine hydrochloride (LID-HCl)-containing semisolid in situ film-forming systems (FFSs) using the Quality by Design (QbD) approach to increase drug permeation into the skin. METHODS: Silicones were used to improve the prope...

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Detalles Bibliográficos
Autores principales: Kovács, Anita, Kis, Nikolett, Budai-Szűcs, Mária, Gácsi, Attila, Csányi, Erzsébet, Csóka, Ildikó, Berkó, Szilvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680691/
https://www.ncbi.nlm.nih.gov/pubmed/33239865
http://dx.doi.org/10.2147/DDDT.S279727

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680691/
https://www.ncbi.nlm.nih.gov/pubmed/33239865
http://dx.doi.org/10.2147/DDDT.S279727

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