Cargando…

γ-Aminobutyric acid found in fermented foods and beverages: current trends

γ-aminobutyric acid (GABA) is synthesised by glutamic acid decarboxylase which catalyses the decarboxylation of L-glutamic acid. L-glutamic acid is formed by α-ketoglutarate in the TCA cycle by glutamic acid dehydrogenase (GDH). GABA is found in the human brain, plants, animals and microorganisms. G...

Descripción completa

Detalles Bibliográficos
Autores principales: Sahab, Novia R.M., Subroto, Edy, Balia, Roostita L., Utama, Gemilang L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680766/
https://www.ncbi.nlm.nih.gov/pubmed/33251370
http://dx.doi.org/10.1016/j.heliyon.2020.e05526
_version_ 1783612498870534144
author Sahab, Novia R.M.
Subroto, Edy
Balia, Roostita L.
Utama, Gemilang L.
author_facet Sahab, Novia R.M.
Subroto, Edy
Balia, Roostita L.
Utama, Gemilang L.
author_sort Sahab, Novia R.M.
collection PubMed
description γ-aminobutyric acid (GABA) is synthesised by glutamic acid decarboxylase which catalyses the decarboxylation of L-glutamic acid. L-glutamic acid is formed by α-ketoglutarate in the TCA cycle by glutamic acid dehydrogenase (GDH). GABA is found in the human brain, plants, animals and microorganisms. GABA functions as an antidepressant, antihypertensive, antidiabetic and immune system enhancer and has a good effect on neural disease. As GABA have pharmaceutical properties, conditions for GABA production need to be established. Microbiological GABA production is more safe and eco-friendly rather than chemical methods. Moreover, it is easier to control conditions of production using microorganisms compared to production in plants and animals. GABA production in fermented foods and beverages has the potential to be optimised to increase the functional effect of fermented foods and beverages.
format Online
Article
Text
id pubmed-7680766
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-76807662020-11-27 γ-Aminobutyric acid found in fermented foods and beverages: current trends Sahab, Novia R.M. Subroto, Edy Balia, Roostita L. Utama, Gemilang L. Heliyon Review Article γ-aminobutyric acid (GABA) is synthesised by glutamic acid decarboxylase which catalyses the decarboxylation of L-glutamic acid. L-glutamic acid is formed by α-ketoglutarate in the TCA cycle by glutamic acid dehydrogenase (GDH). GABA is found in the human brain, plants, animals and microorganisms. GABA functions as an antidepressant, antihypertensive, antidiabetic and immune system enhancer and has a good effect on neural disease. As GABA have pharmaceutical properties, conditions for GABA production need to be established. Microbiological GABA production is more safe and eco-friendly rather than chemical methods. Moreover, it is easier to control conditions of production using microorganisms compared to production in plants and animals. GABA production in fermented foods and beverages has the potential to be optimised to increase the functional effect of fermented foods and beverages. Elsevier 2020-11-16 /pmc/articles/PMC7680766/ /pubmed/33251370 http://dx.doi.org/10.1016/j.heliyon.2020.e05526 Text en © 2020 Published by Elsevier Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
Sahab, Novia R.M.
Subroto, Edy
Balia, Roostita L.
Utama, Gemilang L.
γ-Aminobutyric acid found in fermented foods and beverages: current trends
title γ-Aminobutyric acid found in fermented foods and beverages: current trends
title_full γ-Aminobutyric acid found in fermented foods and beverages: current trends
title_fullStr γ-Aminobutyric acid found in fermented foods and beverages: current trends
title_full_unstemmed γ-Aminobutyric acid found in fermented foods and beverages: current trends
title_short γ-Aminobutyric acid found in fermented foods and beverages: current trends
title_sort γ-aminobutyric acid found in fermented foods and beverages: current trends
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680766/
https://www.ncbi.nlm.nih.gov/pubmed/33251370
http://dx.doi.org/10.1016/j.heliyon.2020.e05526
work_keys_str_mv AT sahabnoviarm gaminobutyricacidfoundinfermentedfoodsandbeveragescurrenttrends
AT subrotoedy gaminobutyricacidfoundinfermentedfoodsandbeveragescurrenttrends
AT baliaroostital gaminobutyricacidfoundinfermentedfoodsandbeveragescurrenttrends
AT utamagemilangl gaminobutyricacidfoundinfermentedfoodsandbeveragescurrenttrends