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γ-Aminobutyric acid found in fermented foods and beverages: current trends
γ-aminobutyric acid (GABA) is synthesised by glutamic acid decarboxylase which catalyses the decarboxylation of L-glutamic acid. L-glutamic acid is formed by α-ketoglutarate in the TCA cycle by glutamic acid dehydrogenase (GDH). GABA is found in the human brain, plants, animals and microorganisms. G...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680766/ https://www.ncbi.nlm.nih.gov/pubmed/33251370 http://dx.doi.org/10.1016/j.heliyon.2020.e05526 |
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author | Sahab, Novia R.M. Subroto, Edy Balia, Roostita L. Utama, Gemilang L. |
author_facet | Sahab, Novia R.M. Subroto, Edy Balia, Roostita L. Utama, Gemilang L. |
author_sort | Sahab, Novia R.M. |
collection | PubMed |
description | γ-aminobutyric acid (GABA) is synthesised by glutamic acid decarboxylase which catalyses the decarboxylation of L-glutamic acid. L-glutamic acid is formed by α-ketoglutarate in the TCA cycle by glutamic acid dehydrogenase (GDH). GABA is found in the human brain, plants, animals and microorganisms. GABA functions as an antidepressant, antihypertensive, antidiabetic and immune system enhancer and has a good effect on neural disease. As GABA have pharmaceutical properties, conditions for GABA production need to be established. Microbiological GABA production is more safe and eco-friendly rather than chemical methods. Moreover, it is easier to control conditions of production using microorganisms compared to production in plants and animals. GABA production in fermented foods and beverages has the potential to be optimised to increase the functional effect of fermented foods and beverages. |
format | Online Article Text |
id | pubmed-7680766 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-76807662020-11-27 γ-Aminobutyric acid found in fermented foods and beverages: current trends Sahab, Novia R.M. Subroto, Edy Balia, Roostita L. Utama, Gemilang L. Heliyon Review Article γ-aminobutyric acid (GABA) is synthesised by glutamic acid decarboxylase which catalyses the decarboxylation of L-glutamic acid. L-glutamic acid is formed by α-ketoglutarate in the TCA cycle by glutamic acid dehydrogenase (GDH). GABA is found in the human brain, plants, animals and microorganisms. GABA functions as an antidepressant, antihypertensive, antidiabetic and immune system enhancer and has a good effect on neural disease. As GABA have pharmaceutical properties, conditions for GABA production need to be established. Microbiological GABA production is more safe and eco-friendly rather than chemical methods. Moreover, it is easier to control conditions of production using microorganisms compared to production in plants and animals. GABA production in fermented foods and beverages has the potential to be optimised to increase the functional effect of fermented foods and beverages. Elsevier 2020-11-16 /pmc/articles/PMC7680766/ /pubmed/33251370 http://dx.doi.org/10.1016/j.heliyon.2020.e05526 Text en © 2020 Published by Elsevier Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Review Article Sahab, Novia R.M. Subroto, Edy Balia, Roostita L. Utama, Gemilang L. γ-Aminobutyric acid found in fermented foods and beverages: current trends |
title | γ-Aminobutyric acid found in fermented foods and beverages: current trends |
title_full | γ-Aminobutyric acid found in fermented foods and beverages: current trends |
title_fullStr | γ-Aminobutyric acid found in fermented foods and beverages: current trends |
title_full_unstemmed | γ-Aminobutyric acid found in fermented foods and beverages: current trends |
title_short | γ-Aminobutyric acid found in fermented foods and beverages: current trends |
title_sort | γ-aminobutyric acid found in fermented foods and beverages: current trends |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680766/ https://www.ncbi.nlm.nih.gov/pubmed/33251370 http://dx.doi.org/10.1016/j.heliyon.2020.e05526 |
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