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Assessment of Diabetic Retinopathy Vascular Density Maps

PURPOSE: Optical coherence tomography (OCT) and OCTA were used for qualitative and quantitative assessment of retinal vascular density in superficial capillary plexus, deep capillary plexus, foveal avascular zone, and choroidal vascular density map. PATIENTS AND METHODS: This study included 64 eyes....

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Autores principales: Saif, Passant Sayed, Salman, Abd El-Rahman Gaber, Omran, Norhan Amr Hassan, Farweez, Yousra Ahmed Thabet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680795/
https://www.ncbi.nlm.nih.gov/pubmed/33239860
http://dx.doi.org/10.2147/OPTH.S256963
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author Saif, Passant Sayed
Salman, Abd El-Rahman Gaber
Omran, Norhan Amr Hassan
Farweez, Yousra Ahmed Thabet
author_facet Saif, Passant Sayed
Salman, Abd El-Rahman Gaber
Omran, Norhan Amr Hassan
Farweez, Yousra Ahmed Thabet
author_sort Saif, Passant Sayed
collection PubMed
description PURPOSE: Optical coherence tomography (OCT) and OCTA were used for qualitative and quantitative assessment of retinal vascular density in superficial capillary plexus, deep capillary plexus, foveal avascular zone, and choroidal vascular density map. PATIENTS AND METHODS: This study included 64 eyes. Diabetics and control groups were recruited from an internal medicine clinic at Misr University for Science and Technology Hospital and asked to participate in this study. This study was designed as an observational and cross-sectional study in the period from 8/2018 to 8/2019. RESULTS: There was a decrease in choroidal vascular density in diabetic patients. There was a decrease in retinal thickness in diabetic patients and there were no significant differences in the retinal thickness between control subjects and patients with non-diabetic retinopathy (NDR). CONCLUSION: Our study suggests that OCTA can identify preclinical DR before the manifestation of clinically apparent retinopathy. Our findings also highlight the potential role of OCTA in monitoring and quantifying retinal vascular alterations in diabetics.
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spelling pubmed-76807952020-11-24 Assessment of Diabetic Retinopathy Vascular Density Maps Saif, Passant Sayed Salman, Abd El-Rahman Gaber Omran, Norhan Amr Hassan Farweez, Yousra Ahmed Thabet Clin Ophthalmol Original Research PURPOSE: Optical coherence tomography (OCT) and OCTA were used for qualitative and quantitative assessment of retinal vascular density in superficial capillary plexus, deep capillary plexus, foveal avascular zone, and choroidal vascular density map. PATIENTS AND METHODS: This study included 64 eyes. Diabetics and control groups were recruited from an internal medicine clinic at Misr University for Science and Technology Hospital and asked to participate in this study. This study was designed as an observational and cross-sectional study in the period from 8/2018 to 8/2019. RESULTS: There was a decrease in choroidal vascular density in diabetic patients. There was a decrease in retinal thickness in diabetic patients and there were no significant differences in the retinal thickness between control subjects and patients with non-diabetic retinopathy (NDR). CONCLUSION: Our study suggests that OCTA can identify preclinical DR before the manifestation of clinically apparent retinopathy. Our findings also highlight the potential role of OCTA in monitoring and quantifying retinal vascular alterations in diabetics. Dove 2020-11-17 /pmc/articles/PMC7680795/ /pubmed/33239860 http://dx.doi.org/10.2147/OPTH.S256963 Text en © 2020 Saif et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Saif, Passant Sayed
Salman, Abd El-Rahman Gaber
Omran, Norhan Amr Hassan
Farweez, Yousra Ahmed Thabet
Assessment of Diabetic Retinopathy Vascular Density Maps
title Assessment of Diabetic Retinopathy Vascular Density Maps
title_full Assessment of Diabetic Retinopathy Vascular Density Maps
title_fullStr Assessment of Diabetic Retinopathy Vascular Density Maps
title_full_unstemmed Assessment of Diabetic Retinopathy Vascular Density Maps
title_short Assessment of Diabetic Retinopathy Vascular Density Maps
title_sort assessment of diabetic retinopathy vascular density maps
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680795/
https://www.ncbi.nlm.nih.gov/pubmed/33239860
http://dx.doi.org/10.2147/OPTH.S256963
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