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Assessment of Diabetic Retinopathy Vascular Density Maps
PURPOSE: Optical coherence tomography (OCT) and OCTA were used for qualitative and quantitative assessment of retinal vascular density in superficial capillary plexus, deep capillary plexus, foveal avascular zone, and choroidal vascular density map. PATIENTS AND METHODS: This study included 64 eyes....
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680795/ https://www.ncbi.nlm.nih.gov/pubmed/33239860 http://dx.doi.org/10.2147/OPTH.S256963 |
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author | Saif, Passant Sayed Salman, Abd El-Rahman Gaber Omran, Norhan Amr Hassan Farweez, Yousra Ahmed Thabet |
author_facet | Saif, Passant Sayed Salman, Abd El-Rahman Gaber Omran, Norhan Amr Hassan Farweez, Yousra Ahmed Thabet |
author_sort | Saif, Passant Sayed |
collection | PubMed |
description | PURPOSE: Optical coherence tomography (OCT) and OCTA were used for qualitative and quantitative assessment of retinal vascular density in superficial capillary plexus, deep capillary plexus, foveal avascular zone, and choroidal vascular density map. PATIENTS AND METHODS: This study included 64 eyes. Diabetics and control groups were recruited from an internal medicine clinic at Misr University for Science and Technology Hospital and asked to participate in this study. This study was designed as an observational and cross-sectional study in the period from 8/2018 to 8/2019. RESULTS: There was a decrease in choroidal vascular density in diabetic patients. There was a decrease in retinal thickness in diabetic patients and there were no significant differences in the retinal thickness between control subjects and patients with non-diabetic retinopathy (NDR). CONCLUSION: Our study suggests that OCTA can identify preclinical DR before the manifestation of clinically apparent retinopathy. Our findings also highlight the potential role of OCTA in monitoring and quantifying retinal vascular alterations in diabetics. |
format | Online Article Text |
id | pubmed-7680795 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-76807952020-11-24 Assessment of Diabetic Retinopathy Vascular Density Maps Saif, Passant Sayed Salman, Abd El-Rahman Gaber Omran, Norhan Amr Hassan Farweez, Yousra Ahmed Thabet Clin Ophthalmol Original Research PURPOSE: Optical coherence tomography (OCT) and OCTA were used for qualitative and quantitative assessment of retinal vascular density in superficial capillary plexus, deep capillary plexus, foveal avascular zone, and choroidal vascular density map. PATIENTS AND METHODS: This study included 64 eyes. Diabetics and control groups were recruited from an internal medicine clinic at Misr University for Science and Technology Hospital and asked to participate in this study. This study was designed as an observational and cross-sectional study in the period from 8/2018 to 8/2019. RESULTS: There was a decrease in choroidal vascular density in diabetic patients. There was a decrease in retinal thickness in diabetic patients and there were no significant differences in the retinal thickness between control subjects and patients with non-diabetic retinopathy (NDR). CONCLUSION: Our study suggests that OCTA can identify preclinical DR before the manifestation of clinically apparent retinopathy. Our findings also highlight the potential role of OCTA in monitoring and quantifying retinal vascular alterations in diabetics. Dove 2020-11-17 /pmc/articles/PMC7680795/ /pubmed/33239860 http://dx.doi.org/10.2147/OPTH.S256963 Text en © 2020 Saif et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Original Research Saif, Passant Sayed Salman, Abd El-Rahman Gaber Omran, Norhan Amr Hassan Farweez, Yousra Ahmed Thabet Assessment of Diabetic Retinopathy Vascular Density Maps |
title | Assessment of Diabetic Retinopathy Vascular Density Maps |
title_full | Assessment of Diabetic Retinopathy Vascular Density Maps |
title_fullStr | Assessment of Diabetic Retinopathy Vascular Density Maps |
title_full_unstemmed | Assessment of Diabetic Retinopathy Vascular Density Maps |
title_short | Assessment of Diabetic Retinopathy Vascular Density Maps |
title_sort | assessment of diabetic retinopathy vascular density maps |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680795/ https://www.ncbi.nlm.nih.gov/pubmed/33239860 http://dx.doi.org/10.2147/OPTH.S256963 |
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