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Initial Outcomes with Customized Myopic LASIK, Guided by Automated Ray Tracing Optimization: A Novel Technique

PURPOSE: Safety and efficacy of a novel automated ray tracing optimization in customization of excimer ablation in myopic LASIK. METHODS: In a consecutive case series, 25 patients (50 eyes) undergoing femtosecond-laser-assisted myopic LASIK were evaluated. The novel, artificial-intelligence platform...

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Autor principal: Kanellopoulos, Anastasios John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680798/
https://www.ncbi.nlm.nih.gov/pubmed/33239861
http://dx.doi.org/10.2147/OPTH.S280560
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author Kanellopoulos, Anastasios John
author_facet Kanellopoulos, Anastasios John
author_sort Kanellopoulos, Anastasios John
collection PubMed
description PURPOSE: Safety and efficacy of a novel automated ray tracing optimization in customization of excimer ablation in myopic LASIK. METHODS: In a consecutive case series, 25 patients (50 eyes) undergoing femtosecond-laser-assisted myopic LASIK were evaluated. The novel, artificial-intelligence platform initially calculates the ablation profile based on a model eye for each case, based on interferometry axial length data. Low- and high-order aberration calculation is performed by raytracing based on wavefront and Scheimpflug tomography measurements, all from a single diagnostic device. Visual acuity, refractive error, keratometry, topography, high-order aberrations and contrast sensitivity were evaluated, over six months follow-up. RESULTS: Change from pre- to 6 months post-operative: mean refractive error improved from −5.06 ± 2.54 diopters (D) (range −8.0 to −0.50 D) to −0.11 ± 0.09 D (range −0.25 to + 0.25); refractive astigmatism from −1.07 ± 0.91 D (range −4.25 to 0 D) to −0.15 ± 0.04 D (range −0.25 to 0); and topographic astigmatism from −1.65 ± 0.85 D to −0.26 ± 0.11 D (range −0.60 to 0). About 65% of eyes gained one line of vision and 38% 2 lines. Pre- to post-operative high-order aberration average: RMSh changed from 0.25 um to 0.35 um. Contrast sensitivity improved post-operatively. CONCLUSION: We report safe and effective preliminary outcomes with a novel excimer laser customization by ray tracing optimization, for myopic LASIK treatments, employing several independent up-till-now diagnostics and a customized eye model reference for each case. It bears the potential advantage through total eye aberration data and ray tracing refraction calculation to offer improved and more predictable visual outcomes.
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spelling pubmed-76807982020-11-24 Initial Outcomes with Customized Myopic LASIK, Guided by Automated Ray Tracing Optimization: A Novel Technique Kanellopoulos, Anastasios John Clin Ophthalmol Original Research PURPOSE: Safety and efficacy of a novel automated ray tracing optimization in customization of excimer ablation in myopic LASIK. METHODS: In a consecutive case series, 25 patients (50 eyes) undergoing femtosecond-laser-assisted myopic LASIK were evaluated. The novel, artificial-intelligence platform initially calculates the ablation profile based on a model eye for each case, based on interferometry axial length data. Low- and high-order aberration calculation is performed by raytracing based on wavefront and Scheimpflug tomography measurements, all from a single diagnostic device. Visual acuity, refractive error, keratometry, topography, high-order aberrations and contrast sensitivity were evaluated, over six months follow-up. RESULTS: Change from pre- to 6 months post-operative: mean refractive error improved from −5.06 ± 2.54 diopters (D) (range −8.0 to −0.50 D) to −0.11 ± 0.09 D (range −0.25 to + 0.25); refractive astigmatism from −1.07 ± 0.91 D (range −4.25 to 0 D) to −0.15 ± 0.04 D (range −0.25 to 0); and topographic astigmatism from −1.65 ± 0.85 D to −0.26 ± 0.11 D (range −0.60 to 0). About 65% of eyes gained one line of vision and 38% 2 lines. Pre- to post-operative high-order aberration average: RMSh changed from 0.25 um to 0.35 um. Contrast sensitivity improved post-operatively. CONCLUSION: We report safe and effective preliminary outcomes with a novel excimer laser customization by ray tracing optimization, for myopic LASIK treatments, employing several independent up-till-now diagnostics and a customized eye model reference for each case. It bears the potential advantage through total eye aberration data and ray tracing refraction calculation to offer improved and more predictable visual outcomes. Dove 2020-11-17 /pmc/articles/PMC7680798/ /pubmed/33239861 http://dx.doi.org/10.2147/OPTH.S280560 Text en © 2020 Kanellopoulos. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Kanellopoulos, Anastasios John
Initial Outcomes with Customized Myopic LASIK, Guided by Automated Ray Tracing Optimization: A Novel Technique
title Initial Outcomes with Customized Myopic LASIK, Guided by Automated Ray Tracing Optimization: A Novel Technique
title_full Initial Outcomes with Customized Myopic LASIK, Guided by Automated Ray Tracing Optimization: A Novel Technique
title_fullStr Initial Outcomes with Customized Myopic LASIK, Guided by Automated Ray Tracing Optimization: A Novel Technique
title_full_unstemmed Initial Outcomes with Customized Myopic LASIK, Guided by Automated Ray Tracing Optimization: A Novel Technique
title_short Initial Outcomes with Customized Myopic LASIK, Guided by Automated Ray Tracing Optimization: A Novel Technique
title_sort initial outcomes with customized myopic lasik, guided by automated ray tracing optimization: a novel technique
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680798/
https://www.ncbi.nlm.nih.gov/pubmed/33239861
http://dx.doi.org/10.2147/OPTH.S280560
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