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Protective role of microglial HO-1 blockade in aging: Implication of iron metabolism

Heme oxygenase-1 (HO-1) is an inducible enzyme known for its anti-inflammatory, antioxidant and neuroprotective effects. However, increased expression of HO-1 during aging and age-related neurodegenerative diseases have been associated to neurotoxic ferric iron deposits. Being microglia responsible...

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Detalles Bibliográficos
Autores principales:	Fernández-Mendívil, Cristina, Luengo, Enrique, Trigo-Alonso, Paula, García-Magro, Nuria, Negredo, Pilar, López, Manuela G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680814/ https://www.ncbi.nlm.nih.gov/pubmed/33212416 http://dx.doi.org/10.1016/j.redox.2020.101789

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