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Regulation of HCN2 Current by PI3K/Akt Signaling

It has long been known that heart rate is regulated by the autonomic nervous system. Recently, we demonstrated that the pacemaker current, I(f), is regulated by phosphoinositide 3-kinase (PI3K) signaling independently of the autonomic nervous system. Inhibition of PI3K in sinus node (SN) myocytes sh...

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Detalles Bibliográficos
Autores principales:	Lu, Zhongju, Wang, Hong Zhan, Gordon, Chris R., Ballou, Lisa M., Lin, Richard Z., Cohen, Ira S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680966/ https://www.ncbi.nlm.nih.gov/pubmed/33240105 http://dx.doi.org/10.3389/fphys.2020.587040

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