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A Suggested Role of Human Growth Hormone in Control of the COVID-19 Pandemic

Covid19 is a worldwide pandemic challenge that started in Wuhan, China and spread to almost all countries on the planet within a few months. The causative virus was found to be highly contagious and, until now, considerably difficult to contain. A look at the epidemiological distribution of the dise...

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Detalles Bibliográficos
Autores principales: Elkarow, Mohamed Hamdy, Hamdy, Amr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680968/
https://www.ncbi.nlm.nih.gov/pubmed/33240216
http://dx.doi.org/10.3389/fendo.2020.569633
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author Elkarow, Mohamed Hamdy
Hamdy, Amr
author_facet Elkarow, Mohamed Hamdy
Hamdy, Amr
author_sort Elkarow, Mohamed Hamdy
collection PubMed
description Covid19 is a worldwide pandemic challenge that started in Wuhan, China and spread to almost all countries on the planet within a few months. The causative virus was found to be highly contagious and, until now, considerably difficult to contain. A look at the epidemiological distribution of the disease over the planet has raised a number of questions whose answers could help us understand the behavior of the virus and consequently leads us to possible means of limitation of its spread or even flattening of the curve of morbidity and mortality. After the third decade of life, there is a progressive decline of growth hormone (GH) secretion by approximately 15% for every decade of adult life. The data from highly affected countries suggest a more aggressive course in the elderly, a double-time affection of males more than females, and the vulnerability of some risk groups of patients. Our observation is that GH deficiency is a common factor in all vulnerable patient groups. We think that there is a need for studying the role of growth hormone in the unique epidemiological pattern of Covid-19 so that it might help in the early detection and management of the high-risk groups as appropriate.
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spelling pubmed-76809682020-11-24 A Suggested Role of Human Growth Hormone in Control of the COVID-19 Pandemic Elkarow, Mohamed Hamdy Hamdy, Amr Front Endocrinol (Lausanne) Endocrinology Covid19 is a worldwide pandemic challenge that started in Wuhan, China and spread to almost all countries on the planet within a few months. The causative virus was found to be highly contagious and, until now, considerably difficult to contain. A look at the epidemiological distribution of the disease over the planet has raised a number of questions whose answers could help us understand the behavior of the virus and consequently leads us to possible means of limitation of its spread or even flattening of the curve of morbidity and mortality. After the third decade of life, there is a progressive decline of growth hormone (GH) secretion by approximately 15% for every decade of adult life. The data from highly affected countries suggest a more aggressive course in the elderly, a double-time affection of males more than females, and the vulnerability of some risk groups of patients. Our observation is that GH deficiency is a common factor in all vulnerable patient groups. We think that there is a need for studying the role of growth hormone in the unique epidemiological pattern of Covid-19 so that it might help in the early detection and management of the high-risk groups as appropriate. Frontiers Media S.A. 2020-11-09 /pmc/articles/PMC7680968/ /pubmed/33240216 http://dx.doi.org/10.3389/fendo.2020.569633 Text en Copyright © 2020 Elkarow and Hamdy http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Endocrinology
Elkarow, Mohamed Hamdy
Hamdy, Amr
A Suggested Role of Human Growth Hormone in Control of the COVID-19 Pandemic
title A Suggested Role of Human Growth Hormone in Control of the COVID-19 Pandemic
title_full A Suggested Role of Human Growth Hormone in Control of the COVID-19 Pandemic
title_fullStr A Suggested Role of Human Growth Hormone in Control of the COVID-19 Pandemic
title_full_unstemmed A Suggested Role of Human Growth Hormone in Control of the COVID-19 Pandemic
title_short A Suggested Role of Human Growth Hormone in Control of the COVID-19 Pandemic
title_sort suggested role of human growth hormone in control of the covid-19 pandemic
topic Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680968/
https://www.ncbi.nlm.nih.gov/pubmed/33240216
http://dx.doi.org/10.3389/fendo.2020.569633
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