Age‐induced mitochondrial DNA point mutations are inadequate to alter metabolic homeostasis in response to nutrient challenge

Mitochondrial dysfunction is frequently associated with impairment in metabolic homeostasis and insulin action, and is thought to underlie cellular aging. However, it is unclear whether mitochondrial dysfunction is a cause or consequence of insulin resistance in humans. To determine the impact of in...

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Detalles Bibliográficos
Autores principales: Moore, Timothy M., Zhou, Zhenqi, Strumwasser, Alexander R., Cohn, Whitaker, Lin, Amanda J., Cory, Kevin, Whitney, Kate, Ho, Theodore, Ho, Timothy, Lee, Joseph L., Rucker, Daniel H., Hoang, Austin N., Widjaja, Kevin, Abrishami, Aaron D., Charugundla, Sarada, Stiles, Linsey, Whitelegge, Julian P., Turcotte, Lorraine P., Wanagat, Jonathan, Hevener, Andrea L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681042/
https://www.ncbi.nlm.nih.gov/pubmed/33049094
http://dx.doi.org/10.1111/acel.13166

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