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miR‐195 reduces age‐related blood–brain barrier leakage caused by thrombospondin‐1‐mediated selective autophagy

Blood–brain barrier (BBB) disruption contributes to neurodegenerative diseases. Loss of tight junction (TJ) proteins in cerebral endothelial cells (ECs) is a leading cause of BBB breakdown. We recently reported that miR‐195 provides vasoprotection, which urges us to explore the role of miR‐195 in BB...

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Detalles Bibliográficos
Autores principales: Chen, Chien‐Yuan, Chao, Yung‐Mei, Lin, Hsiu‐Fen, Chen, Chao‐Jung, Chen, Cheng‐Sheng, Yang, Jenq‐Lin, Chan, Julie Y. H., Juo, Suh‐Hang H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681043/
https://www.ncbi.nlm.nih.gov/pubmed/33029941
http://dx.doi.org/10.1111/acel.13236