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Premature aging syndrome showing random chromosome number instabilities with CDC20 mutation

Damage to the genome can accelerate aging. The percentage of aneuploid cells, that is, cells with an abnormal number of chromosomes, increases during aging; however, it is not clear whether increased aneuploidy accelerates aging. Here, we report an individual showing premature aging phenotypes of va...

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Detalles Bibliográficos
Autores principales:	Fujita, Harumi, Sasaki, Takashi, Miyamoto, Tatsuo, Akutsu, Silvia Natsuko, Sato, Showbu, Mori, Takehiko, Nakabayashi, Kazuhiko, Hata, Kenichiro, Suzuki, Hisato, Kosaki, Kenjiro, Matsuura, Shinya, Matsubara, Yoichi, Amagai, Masayuki, Kubo, Akiharu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681047/ https://www.ncbi.nlm.nih.gov/pubmed/33094908 http://dx.doi.org/10.1111/acel.13251

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