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How age and infection history shape the antigen‐specific CD8(+) T‐cell repertoire: Implications for vaccination strategies in older adults
Older adults often show signs of impaired CD8(+) T‐cell immunity, reflected by weaker responses against new infections and vaccinations, and decreased protection against reinfection. This immune impairment is in part thought to be the consequence of a decrease in both T‐cell numbers and repertoire d...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681067/ https://www.ncbi.nlm.nih.gov/pubmed/33078890 http://dx.doi.org/10.1111/acel.13262 |