Cargando…

How age and infection history shape the antigen‐specific CD8(+) T‐cell repertoire: Implications for vaccination strategies in older adults

Older adults often show signs of impaired CD8(+) T‐cell immunity, reflected by weaker responses against new infections and vaccinations, and decreased protection against reinfection. This immune impairment is in part thought to be the consequence of a decrease in both T‐cell numbers and repertoire d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lanfermeijer, Josien, Borghans, José A. M., van Baarle, Debbie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681067/ https://www.ncbi.nlm.nih.gov/pubmed/33078890 http://dx.doi.org/10.1111/acel.13262

Ejemplares similares

Age and CMV-Infection Jointly Affect the EBV-Specific CD8(+) T-Cell Repertoire
por: Lanfermeijer, Josien, et al.
Publicado: (2021)

The hallmarks of CMV-specific CD8 T-cell differentiation
por: van den Berg, Sara P. H., et al.
Publicado: (2019)

On the feasibility of using TCR sequencing to follow a vaccination response – lessons learned
por: de Greef, Peter C., et al.
Publicado: (2023)

Antigen-dependent competition shapes the local repertoire of tissue-resident memory CD8(+) T cells
por: Muschaweckh, Andreas, et al.
Publicado: (2016)

Longitudinal Characterization of the Mumps-Specific HLA-A2 Restricted T-Cell Response after Mumps Virus Infection
por: Lanfermeijer, Josien, et al.
Publicado: (2021)

Modified influenza M1(58–66) peptide vaccination induces non-relevant T-cells and may enhance pathology after challenge
por: Lanfermeijer, Josien, et al.
Publicado: (2023)

Naive CD8(+) T-cell precursors display structured TCR repertoires and composite antigen-driven selection dynamics
por: Neller, Michelle A, et al.
Publicado: (2015)

Immunoproteasomes Shape Immunodominance Hierarchies of Antiviral Cd8(+) T Cells at the Levels of T Cell Repertoire and Presentation of Viral Antigens
por: Chen, Weisan, et al.
Publicado: (2001)

Microbiome Shapes the T Cell Receptor Repertoire among CD4+CD8+ Thymocytes
por: Surman, Sherri L., et al.
Publicado: (2022)

Latent CMV Infection Is Associated With Lower Influenza Virus-Specific Memory T-Cell Frequencies, but Not With an Impaired T-Cell Response to Acute Influenza Virus Infection
por: van den Berg, Sara P. H., et al.
Publicado: (2021)

Abundance of Early Functional HIV-Specific CD8(+) T Cells Does Not Predict AIDS-Free Survival Time
por: Schellens, Ingrid M. M., et al.
Publicado: (2008)

Quantification of T-cell dynamics during latent cytomegalovirus infection in humans
por: van den Berg, Sara P. H., et al.
Publicado: (2021)

The role of antigen expression in shaping the repertoire of HLA presented ligands
por: Garcia Alvarez, Heli M., et al.
Publicado: (2022)

SARS-CoV-2 antigen exposure history shapes phenotypes and specificity of memory CD8 T cells
por: Minervina, Anastasia A., et al.
Publicado: (2022)

SARS-CoV-2 antigen exposure history shapes phenotypes and specificity of memory CD8 T cells
por: Minervina, Anastasia A., et al.
Publicado: (2022)

Editorial: Role of HLA and KIR in Viral Infections
por: de Wit, Jelle, et al.
Publicado: (2016)

CD8+ T-Cell Repertoire in Human Leukocyte Antigen Class I-Mismatched Alloreactive Immune Response
por: Bettens, Florence, et al.
Publicado: (2021)

Dietary protein shapes the profile and repertoire of intestinal CD4(+) T cells
por: Lockhart, Ainsley, et al.
Publicado: (2023)

Tissue-specific shaping of the TCR repertoire and antigen specificity of iNKT cells
por: Jimeno, Rebeca, et al.
Publicado: (2019)

Proinsulin Expression Shapes the TCR Repertoire but Fails to Control the Development of Low-Avidity Insulin-Reactive CD8(+) T Cells
por: Pearson, James A., et al.
Publicado: (2016)

Towards new horizons: characterization, classification and implications of the tumour antigenic repertoire
por: Haen, Sebastian P., et al.
Publicado: (2020)

Correction: Tissue-specific shaping of the TCR repertoire and antigen specificity of iNKT cells
por: Jimeno, Rebeca, et al.
Publicado: (2020)

Specific CD8(+) TCR Repertoire Recognizing Conserved Antigens of SARS-CoV-2 in Unexposed Population: A Prerequisite for Broad-Spectrum CD8(+) T Cell Immunity
por: Hu, Wei, et al.
Publicado: (2021)

The antigen-specific CD8(+) T cell repertoire in unimmunized mice includes memory phenotype cells bearing markers of homeostatic expansion
por: Haluszczak, Catherine, et al.
Publicado: (2009)

TCR repertoire profiling revealed antigen-driven CD8+ T cell clonal groups shared in synovial fluid of patients with spondyloarthritis
por: Komech, Ekaterina A., et al.
Publicado: (2022)

Association of CD8(+ )T lymphocyte repertoire spreading with the severity of DRESS syndrome
por: Niu, Jun, et al.
Publicado: (2015)

ERAP1 allotypes shape the epitope repertoire of virus-specific CD8(+) T cell responses in acute hepatitis C virus infection
por: Kemming, Janine, et al.
Publicado: (2019)

The Lymph Self-Antigen Repertoire
por: Clement, Cristina C., et al.
Publicado: (2013)

Time and Antigen-Stimulation History Influence Memory CD8 T Cell Bystander Responses
por: Martin, Matthew D., et al.
Publicado: (2017)

Immunology repertoire study of pulmonary sarcoidosis T cells in CD4+, CD8+ PBMC and tissue
por: Fu, Yingyun, et al.
Publicado: (2017)

Depletion of polyfunctional CD26(high)CD8(+) T cells repertoire in chronic lymphocytic leukemia
por: Bozorgmehr, Najmeh, et al.
Publicado: (2023)

Proteome Sampling by the HLA Class I Antigen Processing Pathway
por: Hoof, Ilka, et al.
Publicado: (2012)

Immune Activation and Collateral Damage in AIDS Pathogenesis
por: Miedema, Frank, et al.
Publicado: (2013)

T cell receptor repertoire in polymyositis: clonal expansion of autoaggressive CD8+ T cells
Publicado: (1995)

Decline of influenza-specific CD8(+ )T cell repertoire in healthy geriatric donors
por: Lee, Jessica B, et al.
Publicado: (2011)

Cytomegalovirus Exposure in the Elderly Does Not Reduce CD8 T Cell Repertoire Diversity
por: Lindau, Paul, et al.
Publicado: (2019)

Phantom Plague: How Tuberculosis Shaped History
por: Blumberg, Henry M.
Publicado: (2023)

Antigen delivery to dendritic cells shapes human CD4(+) and CD8(+) T cell memory responses to Staphylococcus aureus
por: Uebele, Julia, et al.
Publicado: (2017)

Repertoire-scale measures of antigen binding
por: Arora, Rohit, et al.
Publicado: (2022)

The Human CD4(+) T Cell Response against Mumps Virus Targets a Broadly Recognized Nucleoprotein Epitope
por: de Wit, Jelle, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_kj5k23q8io2342tuq7f3scmmr6