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IL-37 exerts therapeutic effects in experimental autoimmune encephalomyelitis through the receptor complex IL-1R5/IL-1R8

Background: Interleukin 37 (IL-37), a member of IL-1 family, broadly suppresses inflammation in many pathological conditions by acting as a dual-function cytokine in that IL-37 signals via the extracellular receptor complex IL1-R5/IL-1R8, but it can also translocate to the nucleus. However, whether...

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Detalles Bibliográficos
Autores principales:	Sánchez-Fernández, Alba, Zandee, Stephanie, Amo-Aparicio, Jesús, Charabati, Marc, Prat, Alexandre, Garlanda, Cecilia, Eisenmesser, Elan Z., Dinarello, Charles A., López-Vales, Rubèn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681099/ https://www.ncbi.nlm.nih.gov/pubmed/33391457 http://dx.doi.org/10.7150/thno.47435

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