Cargando…

Evaluation on the use of Nanopore sequencing for direct characterization of coronaviruses from respiratory specimens, and a study on emerging missense mutations in partial RdRP gene of SARS-CoV-2

Coronavirus disease 2019 (COVID-19) pandemic has been a catastrophic burden to global healthcare systems. The fast spread of the etiologic agent, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), highlights the need to identify unknown coronaviruses rapidly for prompt clinical and public...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chan, Wai Sing, Au, Chun Hang, Lam, Ho Yin, Wang, Candy Ling Na, Ho, Dona Ngar-Yin, Lam, Yuk Man, Chu, Daniel Ka Wing, Poon, Leo Lit Man, Chan, Tsun Leung, Zee, Jonpaul Sze-Tsing, Ma, Edmond Shiu Kwan, Tang, Bone Siu Fai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681180/ https://www.ncbi.nlm.nih.gov/pubmed/33225958 http://dx.doi.org/10.1186/s12985-020-01454-3

Ejemplares similares

Genome Sequences of SARS-CoV-2 Strains Detected in Hong Kong
por: Au, Chun Hang, et al.
Publicado: (2020)

Geographical prevalence of SARS-CoV-2 variants, August 2020 to July 2021
por: Chan, Wai Sing, et al.
Publicado: (2022)

RdRp or RT, That is the Question
por: Peyambari, Mahtab, et al.
Publicado: (2021)

Prospective study on human fecal carriage of Enterobacteriaceae possessing mcr-1 and mcr-2 genes in a regional hospital in Hong Kong
por: Chan, Wai-Sing, et al.
Publicado: (2018)

Draft Genome Sequence of Helicobacter cinaedi, Compiled by Direct Whole-Genome Sequencing of a Blood Culture-Positive Isolate in Hong Kong
por: Chan, Wai-Sing, et al.
Publicado: (2018)

Potential utility of targeted Nanopore sequencing for improving etiologic diagnosis of bacterial and fungal respiratory infection
por: Chan, Wai Sing, et al.
Publicado: (2020)

Snapshots of a Non-Canonical RdRP in Action
por: Ferrero, Diego S., et al.
Publicado: (2021)

Aging correlates with lower threshold cycle values for RdRP/RdRP+S genes during molecular detection of SARS-CoV-2
por: Mikuła-Pietrasik, Justyna, et al.
Publicado: (2021)

In silico investigation to identify potential small molecule inhibitors of the RNA-dependent RNA polymerase (RdRp) nidovirus RdRp-associated nucleotidyltransferase domain
por: Pitsillou, Eleni, et al.
Publicado: (2021)

Inhibition of HEV Replication by FDA-Approved RdRp Inhibitors
por: Hooda, Preeti, et al.
Publicado: (2023)

Rapid and economical drug resistance profiling with Nanopore MinION for clinical specimens with low bacillary burden of Mycobacterium tuberculosis
por: Chan, Wai Sing, et al.
Publicado: (2020)

Evaluation of potential anti-RNA-dependent RNA polymerase (RdRP) drugs against the newly emerged model of COVID-19 RdRP using computational methods
por: Poustforoosh, Alireza, et al.
Publicado: (2021)

SARS-CoV-2 RdRp Inhibitors Selected from a Cell-Based SARS-CoV-2 RdRp Activity Assay System
por: Min, Jung Sun, et al.
Publicado: (2021)

RdRp inhibitors and COVID-19: Is molnupiravir a good option?
por: Hashemian, Seyed Mohammad Reza, et al.
Publicado: (2022)

Antiviral Protection via RdRP-Mediated Stable Activation of Innate Immunity
por: Painter, Meghan M., et al.
Publicado: (2015)

RdRp mutations are associated with SARS-CoV-2 genome evolution
por: Eskier, Doğa, et al.
Publicado: (2020)

The potential of Paritaprevir and Emetine as inhibitors of SARS-CoV-2 RdRp
por: Gurung, Arun Bahadur, et al.
Publicado: (2021)

RdRp-based sensitive taxonomic classification of RNA viruses for metagenomic data
por: Tang, Xubo, et al.
Publicado: (2022)

Azelnidipine Exhibits In Vitro and In Vivo Antiviral Effects against Flavivirus Infections by Targeting the Viral RdRp
por: Wang, Zhuang, et al.
Publicado: (2022)

An economical Nanopore sequencing assay for human papillomavirus (HPV) genotyping
por: Chan, Wai Sing, et al.
Publicado: (2020)

Safety and Immunogenicity of a Booster Vaccination by CoronaVac or BNT162b2 in Previously Two-Dose Inactivated Virus Vaccinated Individuals with Negative Neutralizing Antibody
por: Lai, Kristi Tsz-Wan, et al.
Publicado: (2022)

Analysis of the codon usage pattern of the RdRP gene of mycovirus infecting Aspergillus spp.
por: Je, Mikyung, et al.
Publicado: (2019)

Targeting the RdRp of Emerging RNA Viruses: The Structure-Based Drug Design Challenge
por: Picarazzi, Francesca, et al.
Publicado: (2020)

RNA-dependent RNA polymerase (RdRp) natural antiviral inhibitors: a review
por: Leite, Daniela Regina Buch, et al.
Publicado: (2022)

Genomic characteristics and viral load dynamics of a SARS-CoV-2 Omicron BA.2.2 variant from a hospitalized patient treated with molnupiravir
por: Chan, Wai Sing, et al.
Publicado: (2022)

Clinical evaluation of panel testing by next-generation sequencing (NGS) for gene mutations in myeloid neoplasms
por: Au, Chun Hang, et al.
Publicado: (2016)

BAMClipper: removing primers from alignments to minimize false-negative mutations in amplicon next-generation sequencing
por: Au, Chun Hang, et al.
Publicado: (2017)

Evaluation of a Commercial Point-of-Care RT-LAMP Assay for Rapid Detection of SARS-CoV-2
por: Law, Janet Hei Yin, et al.
Publicado: (2023)

Discovery of divided RdRp sequences and a hitherto unknown genomic complexity in fungal viruses
por: Chiba, Yuto, et al.
Publicado: (2020)

In situ structures of polymerase complex of mammalian reovirus illuminate RdRp activation and transcription regulation
por: Bao, Keyan, et al.
Publicado: (2022)

Identification of RNA Virus–Derived RdRp Sequences in Publicly Available Transcriptomic Data Sets
por: Olendraite, Ingrida, et al.
Publicado: (2023)

Development of a Viral RdRp-Assisted Gene Silencing System and Its Application in the Identification of Host Factors of Plant (+)RNA Virus
por: Zhang, Wang, et al.
Publicado: (2021)

Genomic surveillance of Nevada patients revealed prevalence of unique SARS-CoV-2 variants bearing mutations in the RdRp gene
por: Hartley, Paul D., et al.
Publicado: (2020)

Genomic surveillance of Nevada patients revealed prevalence of unique SARS-CoV-2 variants bearing mutations in the RdRp gene
por: Hartley, Paul D., et al.
Publicado: (2021)

Development and validation of RdRp Screen, a crystallization screen for viral RNA-dependent RNA polymerases
por: Riccio, Federica, et al.
Publicado: (2019)

Antibiotic fidaxomicin is an RdRp inhibitor as a potential new therapeutic agent against Zika virus
por: Yuan, Jie, et al.
Publicado: (2020)

Mechanistic insight on the remdesivir binding to RNA-Dependent RNA polymerase (RdRp) of SARS-cov-2
por: Arba, Muhammad, et al.
Publicado: (2021)

RNA-dependent RNA polymerase (RdRp) inhibitors: The current landscape and repurposing for the COVID-19 pandemic
por: Tian, Lei, et al.
Publicado: (2021)

Polyphenols as Potential Inhibitors of SARS-CoV-2 RNA Dependent RNA Polymerase (RdRp)
por: Wu, Yifei, et al.
Publicado: (2021)

Allosteric activation of SARS-CoV-2 RdRp by remdesivir triphosphate and other phosphorylated nucleotides
por: Wang, Bing, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_85oe78rid09cr2p5ccfg721qfe