Cargando…

Cathepsin B is highly expressed in pancreatic cancer stem-like cells and is associated with patients' surgical outcomes

Cancer stem-like cells (CSLCs) in solid tumors are resistant to conventional chemotherapy and molecularly targeted therapy, which is thought to contribute to cancer recurrence and metastasis. The present study aimed to identify biomarkers for pancreatic CSLCs (P-CSLCs). Using our previously reported...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fujimoto, Takuya, Tsunedomi, Ryouichi, Matsukuma, Satoshi, Yoshimura, Kiyoshi, Oga, Atsunori, Fujiwara, Nobuyuki, Fujiwara, Yasuhiro, Matsui, Hiroto, Shindo, Yoshitaro, Tokumitsu, Yukio, Suzuki, Nobuaki, Kobayashi, Shogo, Hazama, Shoichi, Eguchi, Hidetoshi, Nagano, Hiroaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681200/ https://www.ncbi.nlm.nih.gov/pubmed/33240436 http://dx.doi.org/10.3892/ol.2020.12291

Ejemplares similares

Pancreatic Cancer Stem-Like Cells With High Calreticulin Expression Associated With Immune Surveillance
por: Fujiwara, Yasuhiro, et al.
Publicado: (2021)

Elevated expression of RAB3B plays important roles in chemoresistance and metastatic potential of hepatoma cells
por: Tsunedomi, Ryouichi, et al.
Publicado: (2022)

Novel Biomarkers for Personalized Cancer Immunotherapy
por: Shindo, Yoshitaro, et al.
Publicado: (2019)

Association between a single nucleotide polymorphism in the R3HCC1 gene and irinotecan toxicity
por: Kanesada, Kou, et al.
Publicado: (2022)

Calreticulin is highly expressed in pancreatic cancer stem‐like cells
por: Matsukuma, Satoshi, et al.
Publicado: (2016)

Essential updates to the surgical treatment of biliary tract cancer
por: Matsukuma, Satoshi, et al.
Publicado: (2019)

CD4 and FOXP3 as predictive markers for the recurrence of T3/T4a stage II colorectal cancer: applying a novel discrete Bayes decision rule
por: Nakagami, Yuki, et al.
Publicado: (2022)

Siglec-7 is a predictive biomarker for the efficacy of cancer vaccination against metastatic colorectal cancer
por: Yamada, Kensuke, et al.
Publicado: (2021)

Laparoscopic total biopsy for suspected gallbladder cancer: A case series
por: Tokumitsu, Yukio, et al.
Publicado: (2020)

Intratumoural-infiltrating CD4 + and FOXP3 + T cells as strong positive predictive markers for the prognosis of resectable colorectal cancer
por: Kuwahara, Taichi, et al.
Publicado: (2019)

Correction: Intratumoural-infiltrating CD4 + and FOXP3 + T cells as strong positive predictive markers for the prognosis of resectable colorectal cancer
por: Kuwahara, Taichi, et al.
Publicado: (2019)

Laparoscopic Sutureless Rectopexy Using a Fixation Device for Complete Rectal Prolapse
por: Tomochika, Shinobu, et al.
Publicado: (2021)

Surgical shunt ligation for a congenital extrahepatic portosystemic shunt with pulmonary hypertension: A case report
por: Yamada, Kensuke, et al.
Publicado: (2022)

A Phase I Clinical Trial of Vaccination With KIF20A-derived Peptide in Combination With Gemcitabine For Patients With Advanced Pancreatic Cancer
por: Suzuki, Nobuaki, et al.
Publicado: (2014)

Postoperative Adjuvant Therapy for Resectable Pancreatic Cancer With Gemcitabine and Adoptive Immunotherapy
por: Matsui, Hiroto, et al.
Publicado: (2017)

Viral elimination is essential for improving surgical outcomes of hepatitis C virus‐related hepatocellular carcinoma: Multicenter retrospective analysis
por: Nakajima, Masao, et al.
Publicado: (2020)

A novel prediction model of pancreatic fistula after pancreaticoduodenectomy using only preoperative markers
por: Matsui, Hiroto, et al.
Publicado: (2023)

Cancer stem-like sphere cells induced from de-differentiated hepatocellular carcinoma-derived cell lines possess the resistance to anti-cancer drugs
por: Hashimoto, Noriaki, et al.
Publicado: (2014)

Determining the protective characteristics and risk factors for the development of anastomotic leakage after low anterior resection for rectal cancer
por: Suzuki, Nobuaki, et al.
Publicado: (2020)

A stem cell medium containing neural stimulating factor induces a pancreatic cancer stem-like cell-enriched population
por: WATANABE, YUSAKU, et al.
Publicado: (2014)

Cetuximab strongly enhances immune cell infiltration into liver metastatic sites in colorectal cancer
por: Inoue, Yuka, et al.
Publicado: (2017)

Rapid and sensitive detection of UGT1A1 polymorphisms associated with irinotecan toxicity by a novel DNA microarray
por: Tsunedomi, Ryouichi, et al.
Publicado: (2017)

Metastatic ability and the epithelial‐mesenchymal transition in induced cancer stem‐like hepatoma cells
por: Nishiyama, Mitsuo, et al.
Publicado: (2018)

Adoptive immunotherapy with MUC1-mRNA transfected dendritic cells and cytotoxic lymphocytes plus gemcitabine for unresectable pancreatic cancer
por: Shindo, Yoshitaro, et al.
Publicado: (2014)

A phase I study of multi-HLA-binding peptides derived from heat shock protein 70/glypican-3 and a novel combination adjuvant of hLAG-3Ig and Poly-ICLC for patients with metastatic gastrointestinal cancers: YNP01 trial
por: Nakajima, Masao, et al.
Publicado: (2020)

Application and utility of surgical techniques for cystic plate isolation in liver surgery
por: Tokumitsu, Yukio, et al.
Publicado: (2022)

miR-196b, miR-378a and miR-486 are predictive biomarkers for the efficacy of vaccine treatment in colorectal cancer
por: Shindo, Yoshitaro, et al.
Publicado: (2017)

Establishment of a Novel Model for Anticancer Drug Resistance in Three-Dimensional Primary Culture of Tumor Microenvironment
por: Usui, Tatsuya, et al.
Publicado: (2016)

Liver resection with thrombectomy for patients with hepatocellular carcinoma and tumour thrombus in the inferior vena cava or right atrium
por: Matsukuma, S., et al.
Publicado: (2020)

Identification of a Promiscuous Epitope Peptide Derived From HSP70
por: Matsui, Hiroto, et al.
Publicado: (2019)

Outcomes following liver resection for multinodular Barcelona Clinic Liver Cancer-B hepatocellular carcinoma
por: Matsukuma, Satoshi, et al.
Publicado: (2018)

miR‐125b‐1 and miR‐378a are predictive biomarkers for the efficacy of vaccine treatment against colorectal cancer
por: Tanaka, Hironori, et al.
Publicado: (2017)

High secreted protein acidic and rich in cysteine expression in peritumoral fibroblasts predicts better prognosis in patients with resectable gastric cancer
por: Nakajima, Masao, et al.
Publicado: (2018)

Efficacy of intraoperative recurrent laryngeal neuromonitoring during surgery for esophageal cancer
por: Takeda, Shigeru, et al.
Publicado: (2020)

Perioperative Microbiologic Monitoring of Sputum on Postoperative Day One as a Predictor of Pneumonia After Hepatectomy
por: Sakamoto, Kazuhiko, et al.
Publicado: (2015)

Association between polymorphisms in EGFR and tumor response during cetuximab and oxaliplatin-based combination therapy in metastatic colorectal cancer: Analysis of data from two clinical trials
por: Maeda, Hiromichi, et al.
Publicado: (2019)

Hedgehog Signals Mediate Anti-Cancer Drug Resistance in Three-Dimensional Primary Colorectal Cancer Organoid Culture
por: Usui, Tatsuya, et al.
Publicado: (2018)

Expression levels of UL16 binding protein 1 and natural killer group 2 member D affect overall survival in patients with gastric cancer following gastrectomy
por: Kamei, Ryoji, et al.
Publicado: (2018)

Phase II clinical trial of peptide cocktail therapy for patients with advanced pancreatic cancer: VENUS‐PC study
por: Suzuki, Nobuaki, et al.
Publicado: (2016)

Prediction of the efficacy of immunotherapy by measuring the integrity of cell‐free DNA in plasma in colorectal cancer
por: Kitahara, Masahiro, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_g501ii4vfub9vpli1j4hlo7785