Cargando…

Polyphyllin VII suppresses cell proliferation, the cell cycle and cell migration in colorectal cancer

Colorectal cancer (CRC) is one of the most common types of human cancer. However, there is still an urgent need to identify novel treatment strategies for CRC. The present study aimed to validate the potential antitumor effects of polyphyllin VII in CRC. The present study revealed that polyphyllin V...

Descripción completa

Detalles Bibliográficos
Autores principales:	Song, Cheng, Pan, Bo, Yang, Xiao, Tang, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681227/ https://www.ncbi.nlm.nih.gov/pubmed/33240431 http://dx.doi.org/10.3892/ol.2020.12286

Ejemplares similares

A new agent developed by biotransformation of polyphyllin VII inhibits chemoresistance in breast cancer
por: He, Dong-Xu, et al.
Publicado: (2015)

Anti-angiogenesis and anti-metastasis effects of Polyphyllin VII on Hepatocellular carcinoma cells in vitro and in vivo
por: Zhang, Chao, et al.
Publicado: (2021)

Polyphyllin I suppresses proliferation and promotes apoptosis of gastric cancer cell by inhibiting stat3 phosphorylation
por: Han, Jun, et al.
Publicado: (2020)

Polyphyllin VII induces apoptosis in HepG2 cells through ROS-mediated mitochondrial dysfunction and MAPK pathways
por: Zhang, Chao, et al.
Publicado: (2016)

Polyphyllin VII Promotes Apoptosis and Autophagic Cell Death via ROS-Inhibited AKT Activity, and Sensitizes Glioma Cells to Temozolomide
por: Pang, Dejiang, et al.
Publicado: (2019)

Polyphyllin VII induces CTC anoikis to inhibit lung cancer metastasis through EGFR pathway regulation
por: Que, Zujun, et al.
Publicado: (2023)

Polyphyllin I suppresses the gastric cancer growth by promoting cancer cell ferroptosis
por: Zheng, Fang, et al.
Publicado: (2023)

Polyphyllin I and VII potentiate the chemosensitivity of A549/DDP cells to cisplatin by enhancing apoptosis, reversing EMT and suppressing the CIP2A/AKT/mTOR signaling axis
por: Feng, Feifei, et al.
Publicado: (2019)

Corrigendum: Polyphyllin I suppresses the gastric cancer growth by promoting cancer cell ferroptosis
por: Zheng, Fang, et al.
Publicado: (2023)

Targeting macrophage priming by polyphyllin VII triggers anti-tumor immunity via STING-governed cytotoxic T-cell infiltration in lung cancer
por: Yu, Jinglu, et al.
Publicado: (2020)

Polyphyllin VII Induces an Autophagic Cell Death by Activation of the JNK Pathway and Inhibition of PI3K/AKT/mTOR Pathway in HepG2 Cells
por: Zhang, Chao, et al.
Publicado: (2016)

Polyphyllin II inhibits liver cancer cell proliferation, migration and invasion through downregulated cofilin activity and the AKT/NF-κB pathway
por: Pang, Dejiang, et al.
Publicado: (2020)

Promotion of Ros-mediated Bax/Cyt-c apoptosis by polyphyllin II leads to suppress growth and aggression of glioma cells
por: Cheng, Guang, et al.
Publicado: (2021)

In Vitro and In Vivo Anti-Inflammatory Effects of Polyphyllin VII through Downregulating MAPK and NF-κB Pathways
por: Zhang, Chao, et al.
Publicado: (2019)

Natural Polyphyllins (I, II, D, VI, VII) Reverses Cancer Through Apoptosis, Autophagy, Mitophagy, Inflammation, and Necroptosis
por: Ahmad, Bashir, et al.
Publicado: (2021)

Polyphyllin I inhibits the growth of ovarian cancer cells in nude mice
por: Gu, Linhui, et al.
Publicado: (2016)

Correction: Polyphyllin II inhibits liver cancer cell proliferation, migration and invasion through downregulated cofilin activity and the AKT/NF-κB pathway
por: Pang, Dejiang, et al.
Publicado: (2023)

Polyphyllin VII induces apoptotic cell death via inhibition of the PI3K/Akt and NF-κB pathways in A549 human lung cancer cells
por: He, Hao, et al.
Publicado: (2020)

Polyphyllin I induces cell cycle arrest in prostate cancer cells via the upregulation of IL6 and P21 expression
por: Zhang, Denglu, et al.
Publicado: (2019)

Polyphyllin VII induces apoptosis and autophagy via mediating H(2)O(2) levels and the JNK pathway in human osteosarcoma U2OS cells
por: Li, Xiangde, et al.
Publicado: (2021)

The synergistic anticancer effect of formosanin C and polyphyllin VII based on caspase‐mediated cleavage of Beclin1 inhibiting autophagy and promoting apoptosis
por: Cui, Jingxia, et al.
Publicado: (2018)

Engineered Bacteriorhodopsin May Induce Lung Cancer Cell Cycle Arrest and Suppress Their Proliferation and Migration
por: Wong, Chui-Wei, et al.
Publicado: (2021)

Polyphyllin VII induces mitochondrial apoptosis by regulating the PP2A/AKT/DRP1 signaling axis in human ovarian cancer
por: Zhao, Liubiqi, et al.
Publicado: (2021)

Disruption of Colorectal Cancer Network by Polyphyllins Reveals Pivotal Entities with Implications for Chemoimmunotherapy
por: Siripuram, Ram, et al.
Publicado: (2022)

Polyphyllin VI induces apoptosis and autophagy in human osteosarcoma cells by modulation of ROS/JNK activation
por: Yuan, Yong-Liang, et al.
Publicado: (2019)

Polyphyllin B Suppresses Gastric Tumor Growth by Modulating Iron Metabolism and Inducing Ferroptosis
por: Hu, Can, et al.
Publicado: (2023)

Polyphyllin I suppresses the formation of vasculogenic mimicry via Twist1/VE-cadherin pathway
por: Xiao, Ting, et al.
Publicado: (2018)

Polyphyllin VII attenuated RANKL-induced osteoclast differentiation via inhibiting of TRAF6/c-Src/PI3K pathway and ROS production
por: Zhou, Long, et al.
Publicado: (2020)

AIM2 inhibits colorectal cancer cell proliferation and migration through suppression of Gli1
por: Xu, Menglin, et al.
Publicado: (2020)

Polyphyllin II inhibits human bladder cancer migration and invasion by regulating EMT-associated factors and MMPs
por: Niu, Weipin, et al.
Publicado: (2020)

Polyphyllin I induces mitophagic and apoptotic cell death in human breast cancer cells by increasing mitochondrial PINK1 levels
por: Li, Guo-Bing, et al.
Publicado: (2017)

Irisin Suppresses Nicotine-Mediated Atherosclerosis by Attenuating Endothelial Cell Migration, Proliferation, Cell Cycle Arrest, and Cell Senescence
por: Chen, Junye, et al.
Publicado: (2022)

Endocrine therapy inhibits proliferation and migration, promotes apoptosis and suppresses survivin protein expression in colorectal cancer cells
por: Ou, Qing-Jian, et al.
Publicado: (2017)

Downregulation of SOX9 suppresses breast cancer cell proliferation and migration by regulating apoptosis and cell cycle arrest
por: Wang, Yu-Feng, et al.
Publicado: (2021)

Downregulation of Wnt3 Suppresses Colorectal Cancer Development Through Inhibiting Cell Proliferation and Migration
por: Nie, Xiaobo, et al.
Publicado: (2019)

Tetrandrine suppresses proliferation, induces apoptosis, and inhibits migration and invasion in human prostate cancer cells
por: Liu, Wei, et al.
Publicado: (2015)

Hsa_circ_0001696 modulates cell proliferation and migration in colorectal cancer
por: Li, Pei-Fei, et al.
Publicado: (2021)

Interaction Of c-Jun And HOTAIR- Increased Expression Of p21 Converge In Polyphyllin I-Inhibited Growth Of Human Lung Cancer Cells
por: Zhao, YueYang, et al.
Publicado: (2019)

miR-215 suppresses proliferation and migration of non-small cell lung cancer cells
por: Cai, Xiaopan, et al.
Publicado: (2017)

Lithium promotes proliferation and suppresses migration of Schwann cells
por: Gu, Xiao-Kun, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_kn34q2b8qujp33g9n4dim659t7