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Increased HIV in Greater Kinshasa Urban Health Zones: Democratic Republic of Congo (2017–2018)

BACKGROUND: Diagnosis of people living with HIV (PLHIV) is the first step toward achieving the new Fast Track Strategy to end AIDS by 2030: 95-95-95. However, reaching PLHIV is especially difficult in resource-limited settings such as the Democratic Republic of Congo (DRC), where reliable prevalence...

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Autores principales: Pour, Mohammad, James, Linda, Singh, Kamlendra, Mampunza, Samuel, Baer, Franklin, Scott, JoAnna, Berg, Michael G., Rodgers, Mary A., Cloherty, Gavin A., Hackett Jr, John, McArthur, Carole P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682026/
https://www.ncbi.nlm.nih.gov/pubmed/33225968
http://dx.doi.org/10.1186/s12981-020-00322-y
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author Pour, Mohammad
James, Linda
Singh, Kamlendra
Mampunza, Samuel
Baer, Franklin
Scott, JoAnna
Berg, Michael G.
Rodgers, Mary A.
Cloherty, Gavin A.
Hackett Jr, John
McArthur, Carole P.
author_facet Pour, Mohammad
James, Linda
Singh, Kamlendra
Mampunza, Samuel
Baer, Franklin
Scott, JoAnna
Berg, Michael G.
Rodgers, Mary A.
Cloherty, Gavin A.
Hackett Jr, John
McArthur, Carole P.
author_sort Pour, Mohammad
collection PubMed
description BACKGROUND: Diagnosis of people living with HIV (PLHIV) is the first step toward achieving the new Fast Track Strategy to end AIDS by 2030: 95-95-95. However, reaching PLHIV is especially difficult in resource-limited settings such as the Democratic Republic of Congo (DRC), where reliable prevalence data is lacking. This study evaluated the prevalence of HIV in patients in the urban Kinshasa area. METHODS: Individuals seeking healthcare were tested for HIV between February 2017 and July 2018 at existing Kinshasa urban clinics. The study was conducted in two phases. Case finding was optimized in a pilot study phase using a modified cell phone-based Open\Data Kit (ODK) collection system. HIV prevalence was then determined from data obtained between March–July of 2018 from 8320 individuals over the age of 18 years receiving care at one of 47 clinics in Kinshasa. RESULTS: The prevalence of HIV in our study was 11.0% (95% CI 10.3–11.6%) overall and 8.14% in the subset of N = 1240 participants who were healthy mothers seeking prenatal care. These results are in sharp contrast to President's Emergency Plan for AIDS Relief (PEPFAR) estimates of 2.86%, but are consistent with data from surrounding countries. CONCLUSION: While this data is sub-national and reflects an urban healthcare setting, given the large population of Kinshasa and rapidly changing age demographics, the results suggest that HIV prevalence in the DRC is substantially higher than previously reported.
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spelling pubmed-76820262020-11-23 Increased HIV in Greater Kinshasa Urban Health Zones: Democratic Republic of Congo (2017–2018) Pour, Mohammad James, Linda Singh, Kamlendra Mampunza, Samuel Baer, Franklin Scott, JoAnna Berg, Michael G. Rodgers, Mary A. Cloherty, Gavin A. Hackett Jr, John McArthur, Carole P. AIDS Res Ther Research BACKGROUND: Diagnosis of people living with HIV (PLHIV) is the first step toward achieving the new Fast Track Strategy to end AIDS by 2030: 95-95-95. However, reaching PLHIV is especially difficult in resource-limited settings such as the Democratic Republic of Congo (DRC), where reliable prevalence data is lacking. This study evaluated the prevalence of HIV in patients in the urban Kinshasa area. METHODS: Individuals seeking healthcare were tested for HIV between February 2017 and July 2018 at existing Kinshasa urban clinics. The study was conducted in two phases. Case finding was optimized in a pilot study phase using a modified cell phone-based Open\Data Kit (ODK) collection system. HIV prevalence was then determined from data obtained between March–July of 2018 from 8320 individuals over the age of 18 years receiving care at one of 47 clinics in Kinshasa. RESULTS: The prevalence of HIV in our study was 11.0% (95% CI 10.3–11.6%) overall and 8.14% in the subset of N = 1240 participants who were healthy mothers seeking prenatal care. These results are in sharp contrast to President's Emergency Plan for AIDS Relief (PEPFAR) estimates of 2.86%, but are consistent with data from surrounding countries. CONCLUSION: While this data is sub-national and reflects an urban healthcare setting, given the large population of Kinshasa and rapidly changing age demographics, the results suggest that HIV prevalence in the DRC is substantially higher than previously reported. BioMed Central 2020-11-23 /pmc/articles/PMC7682026/ /pubmed/33225968 http://dx.doi.org/10.1186/s12981-020-00322-y Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Pour, Mohammad
James, Linda
Singh, Kamlendra
Mampunza, Samuel
Baer, Franklin
Scott, JoAnna
Berg, Michael G.
Rodgers, Mary A.
Cloherty, Gavin A.
Hackett Jr, John
McArthur, Carole P.
Increased HIV in Greater Kinshasa Urban Health Zones: Democratic Republic of Congo (2017–2018)
title Increased HIV in Greater Kinshasa Urban Health Zones: Democratic Republic of Congo (2017–2018)
title_full Increased HIV in Greater Kinshasa Urban Health Zones: Democratic Republic of Congo (2017–2018)
title_fullStr Increased HIV in Greater Kinshasa Urban Health Zones: Democratic Republic of Congo (2017–2018)
title_full_unstemmed Increased HIV in Greater Kinshasa Urban Health Zones: Democratic Republic of Congo (2017–2018)
title_short Increased HIV in Greater Kinshasa Urban Health Zones: Democratic Republic of Congo (2017–2018)
title_sort increased hiv in greater kinshasa urban health zones: democratic republic of congo (2017–2018)
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682026/
https://www.ncbi.nlm.nih.gov/pubmed/33225968
http://dx.doi.org/10.1186/s12981-020-00322-y
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