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Diesel exhaust impairs TREM2 to dysregulate neuroinflammation

BACKGROUND: Air pollution has been linked to neurodegenerative diseases, including Alzheimer’s disease (AD), and the underlying neuroimmune mechanisms remain poorly understood. TREM2 is a myeloid cell membrane receptor that is a key regulator of disease-associated microglia (DAM) cells, where loss-o...

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Detalles Bibliográficos
Autores principales:	Greve, Hendrik J., Mumaw, Christen L., Messenger, Evan J., Kodavanti, Prasada R. S., Royland, Joyce L., Kodavanti, Urmila P., Block, Michelle L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682066/ https://www.ncbi.nlm.nih.gov/pubmed/33222683 http://dx.doi.org/10.1186/s12974-020-02017-7

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