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WNT4 secreted by tumor tissues promotes tumor progression in colorectal cancer by activation of the Wnt/β-catenin signalling pathway
BACKGROUND: Wingless and Int-related protein (Wnt) ligands are aberrantly expressed in patients with colorectal cancer (CRC). However, the aberrant level of Wnt ligands in serum have not been explored. Here, we aimed to identify the levels of WNT4 in serum and explored its oncogenic role in CRC. MET...
Autores principales: | Yang, Dongmei, Li, Qing, Shang, Renduo, Yao, Liwen, Wu, Lianlian, Zhang, Mengjiao, Zhang, Lihui, Xu, Ming, Lu, Zihua, Zhou, Jie, Huang, Li, Huang, Xiaodong, Cheng, Du, Yang, Yanning, Yu, Honggang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682076/ https://www.ncbi.nlm.nih.gov/pubmed/33222684 http://dx.doi.org/10.1186/s13046-020-01774-w |
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