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Chebulinic acid is a safe and effective antiangiogenic agent in collagen-induced arthritis in mice
BACKGROUND: Although vascular endothelial growth factor-A (VEGF)-induced angiogenesis has been reported to play an important role in the pathogenesis of rheumatoid arthritis (RA), serious side effects, mainly grade 2–3 hypertension, which is commonly observed with currently available anti-VEGF agent...
Autores principales: | Lu, Kai, Iwenofu, O. Hans, Mitra, Rita, Mo, Xiaokui, Dasgupta, Partha Sarathi, Basu, Sujit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682078/ https://www.ncbi.nlm.nih.gov/pubmed/33225986 http://dx.doi.org/10.1186/s13075-020-02370-1 |
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