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Altered Inflammatory Pathway but Unaffected Liver Fibrosis in Mouse Models of Nonalcoholic Steatohepatitis Involving Interleukin-1 Receptor-Associated Kinase 1 Knockout

BACKGROUND: Interleukin-1 receptor-associated kinases (IRAKs) are crucial mediators in the signaling pathways of Toll-like receptors (TLRs)/IL1Rs. Targeting the IRAK4/IRAK1/TRAF6 axis and its associated pathway has therapeutic benefits in liver fibrosis. However, the function of IRAK1 itself in the...

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Detalles Bibliográficos
Autores principales:	Lei, Ying, Yang, Tianxiao, Shan, Aijing, Di, Wei, Dai, Mengyao, Nan, Jingminjie, Liu, Dongxue, Cao, Yanan, Jiang, Xiuli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2020
Materias:	Animal Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682117/ https://www.ncbi.nlm.nih.gov/pubmed/33203828 http://dx.doi.org/10.12659/MSM.926187

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