Cargando…

Evaluating the impact of the Bolsa Familia conditional cash transfer program on premature cardiovascular and all-cause mortality using the 100 million Brazilian cohort: a natural experiment study protocol

INTRODUCTION: Brazil’s Bolsa Familia Program (BFP) is the world’s largest conditional cash transfer scheme. We shall use a large cohort of applicants for different social programmes to evaluate the effect of BFP receipt on premature all-cause and cardiovascular mortality. METHODS AND ANALYSIS: We wi...

Descripción completa

Detalles Bibliográficos
Autores principales: Pescarini, Julia M, Craig, Peter, Allik, Mirjam, Amorim, Leila, Ali, Sanni, Smeeth, Liam, Barreto, Mauricio L, Leyland, Alastair H, Aquino, Estela M L, Katikireddi, Srinivasa Vittal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682454/
https://www.ncbi.nlm.nih.gov/pubmed/33444195
http://dx.doi.org/10.1136/bmjopen-2020-039658
_version_ 1783612689449222144
author Pescarini, Julia M
Craig, Peter
Allik, Mirjam
Amorim, Leila
Ali, Sanni
Smeeth, Liam
Barreto, Mauricio L
Leyland, Alastair H
Aquino, Estela M L
Katikireddi, Srinivasa Vittal
author_facet Pescarini, Julia M
Craig, Peter
Allik, Mirjam
Amorim, Leila
Ali, Sanni
Smeeth, Liam
Barreto, Mauricio L
Leyland, Alastair H
Aquino, Estela M L
Katikireddi, Srinivasa Vittal
author_sort Pescarini, Julia M
collection PubMed
description INTRODUCTION: Brazil’s Bolsa Familia Program (BFP) is the world’s largest conditional cash transfer scheme. We shall use a large cohort of applicants for different social programmes to evaluate the effect of BFP receipt on premature all-cause and cardiovascular mortality. METHODS AND ANALYSIS: We will identify BFP recipients and non-recipients among new applicants from 2004 to 2015 in the 100 Million Brazilian Cohort, a database of 114 million individuals containing sociodemographic and mortality information of applicants to any Brazilian social programme. For individuals applying from 2011, when we have better recorded income data, we shall compare premature (age 30–69) cardiovascular and all-cause mortality among BFP recipients and non-recipients using regression discontinuity design (RDD) with household monthly per capita income as the forcing variable. Effects will be estimated using survival models accounting for individuals follow-up. To test the sensitivity of our findings, we will estimate models with different bandwidths, include potential confounders as covariates in the survival models, and restrict our data to locations with the most reliable data. In addition, we will estimate the effect of BFP on studied outcomes using propensity score risk-set matching, separately for individuals that applied ≤2010 and >2011, allowing comparability with RDD. Analyses will be stratified by geographical region, gender, race/ethnicity and socioeconomic position. We will investigate differential impacts of BFP and the presence of effect modification for a combination of characteristics, including gender and race/ethnicity. ETHICS AND DISSEMINATION: The study was approved by the ethics committees of Oswaldo Cruz Foundation and the University of Glasgow College of Medicine and Veterinary Life Sciences. The deidentified dataset will be provided to researchers, and data analysis will be performed in a safe computational environment without internet access. Study findings will be published in high quality peer-reviewed research articles. The published results will be disseminated in the social media and to policy-makers.
format Online
Article
Text
id pubmed-7682454
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher BMJ Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-76824542020-11-24 Evaluating the impact of the Bolsa Familia conditional cash transfer program on premature cardiovascular and all-cause mortality using the 100 million Brazilian cohort: a natural experiment study protocol Pescarini, Julia M Craig, Peter Allik, Mirjam Amorim, Leila Ali, Sanni Smeeth, Liam Barreto, Mauricio L Leyland, Alastair H Aquino, Estela M L Katikireddi, Srinivasa Vittal BMJ Open Public Health INTRODUCTION: Brazil’s Bolsa Familia Program (BFP) is the world’s largest conditional cash transfer scheme. We shall use a large cohort of applicants for different social programmes to evaluate the effect of BFP receipt on premature all-cause and cardiovascular mortality. METHODS AND ANALYSIS: We will identify BFP recipients and non-recipients among new applicants from 2004 to 2015 in the 100 Million Brazilian Cohort, a database of 114 million individuals containing sociodemographic and mortality information of applicants to any Brazilian social programme. For individuals applying from 2011, when we have better recorded income data, we shall compare premature (age 30–69) cardiovascular and all-cause mortality among BFP recipients and non-recipients using regression discontinuity design (RDD) with household monthly per capita income as the forcing variable. Effects will be estimated using survival models accounting for individuals follow-up. To test the sensitivity of our findings, we will estimate models with different bandwidths, include potential confounders as covariates in the survival models, and restrict our data to locations with the most reliable data. In addition, we will estimate the effect of BFP on studied outcomes using propensity score risk-set matching, separately for individuals that applied ≤2010 and >2011, allowing comparability with RDD. Analyses will be stratified by geographical region, gender, race/ethnicity and socioeconomic position. We will investigate differential impacts of BFP and the presence of effect modification for a combination of characteristics, including gender and race/ethnicity. ETHICS AND DISSEMINATION: The study was approved by the ethics committees of Oswaldo Cruz Foundation and the University of Glasgow College of Medicine and Veterinary Life Sciences. The deidentified dataset will be provided to researchers, and data analysis will be performed in a safe computational environment without internet access. Study findings will be published in high quality peer-reviewed research articles. The published results will be disseminated in the social media and to policy-makers. BMJ Publishing Group 2020-11-20 /pmc/articles/PMC7682454/ /pubmed/33444195 http://dx.doi.org/10.1136/bmjopen-2020-039658 Text en © Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ. https://creativecommons.org/licenses/by/4.0/ https://creativecommons.org/licenses/by/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.
spellingShingle Public Health
Pescarini, Julia M
Craig, Peter
Allik, Mirjam
Amorim, Leila
Ali, Sanni
Smeeth, Liam
Barreto, Mauricio L
Leyland, Alastair H
Aquino, Estela M L
Katikireddi, Srinivasa Vittal
Evaluating the impact of the Bolsa Familia conditional cash transfer program on premature cardiovascular and all-cause mortality using the 100 million Brazilian cohort: a natural experiment study protocol
title Evaluating the impact of the Bolsa Familia conditional cash transfer program on premature cardiovascular and all-cause mortality using the 100 million Brazilian cohort: a natural experiment study protocol
title_full Evaluating the impact of the Bolsa Familia conditional cash transfer program on premature cardiovascular and all-cause mortality using the 100 million Brazilian cohort: a natural experiment study protocol
title_fullStr Evaluating the impact of the Bolsa Familia conditional cash transfer program on premature cardiovascular and all-cause mortality using the 100 million Brazilian cohort: a natural experiment study protocol
title_full_unstemmed Evaluating the impact of the Bolsa Familia conditional cash transfer program on premature cardiovascular and all-cause mortality using the 100 million Brazilian cohort: a natural experiment study protocol
title_short Evaluating the impact of the Bolsa Familia conditional cash transfer program on premature cardiovascular and all-cause mortality using the 100 million Brazilian cohort: a natural experiment study protocol
title_sort evaluating the impact of the bolsa familia conditional cash transfer program on premature cardiovascular and all-cause mortality using the 100 million brazilian cohort: a natural experiment study protocol
topic Public Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682454/
https://www.ncbi.nlm.nih.gov/pubmed/33444195
http://dx.doi.org/10.1136/bmjopen-2020-039658
work_keys_str_mv AT pescarinijuliam evaluatingtheimpactofthebolsafamiliaconditionalcashtransferprogramonprematurecardiovascularandallcausemortalityusingthe100millionbraziliancohortanaturalexperimentstudyprotocol
AT craigpeter evaluatingtheimpactofthebolsafamiliaconditionalcashtransferprogramonprematurecardiovascularandallcausemortalityusingthe100millionbraziliancohortanaturalexperimentstudyprotocol
AT allikmirjam evaluatingtheimpactofthebolsafamiliaconditionalcashtransferprogramonprematurecardiovascularandallcausemortalityusingthe100millionbraziliancohortanaturalexperimentstudyprotocol
AT amorimleila evaluatingtheimpactofthebolsafamiliaconditionalcashtransferprogramonprematurecardiovascularandallcausemortalityusingthe100millionbraziliancohortanaturalexperimentstudyprotocol
AT alisanni evaluatingtheimpactofthebolsafamiliaconditionalcashtransferprogramonprematurecardiovascularandallcausemortalityusingthe100millionbraziliancohortanaturalexperimentstudyprotocol
AT smeethliam evaluatingtheimpactofthebolsafamiliaconditionalcashtransferprogramonprematurecardiovascularandallcausemortalityusingthe100millionbraziliancohortanaturalexperimentstudyprotocol
AT barretomauriciol evaluatingtheimpactofthebolsafamiliaconditionalcashtransferprogramonprematurecardiovascularandallcausemortalityusingthe100millionbraziliancohortanaturalexperimentstudyprotocol
AT leylandalastairh evaluatingtheimpactofthebolsafamiliaconditionalcashtransferprogramonprematurecardiovascularandallcausemortalityusingthe100millionbraziliancohortanaturalexperimentstudyprotocol
AT aquinoestelaml evaluatingtheimpactofthebolsafamiliaconditionalcashtransferprogramonprematurecardiovascularandallcausemortalityusingthe100millionbraziliancohortanaturalexperimentstudyprotocol
AT katikireddisrinivasavittal evaluatingtheimpactofthebolsafamiliaconditionalcashtransferprogramonprematurecardiovascularandallcausemortalityusingthe100millionbraziliancohortanaturalexperimentstudyprotocol