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Tocilizumab Use in a Chronic Hemodialysis Patient for the Management of COVID-19-Associated Pneumonia and Acute Respiratory Distress Syndrome

Novel coronavirus disease 2019 (COVID-19) is a highly infectious, rapidly spreading viral disease. As of writing this article, there are over 4.4 million people affected by COVID-19, and unfortunately, 300,000 have succumbed to the infection. In this article, we address a particularly more susceptib...

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Autores principales: Gupta, Sudeendra, Madhyastha, Rakesh, Hamed, Fadi, Balkis, Maher, El Nekidy, Wasim, Attallah, Nizar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682475/
https://www.ncbi.nlm.nih.gov/pubmed/33299621
http://dx.doi.org/10.1155/2020/8829309
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author Gupta, Sudeendra
Madhyastha, Rakesh
Hamed, Fadi
Balkis, Maher
El Nekidy, Wasim
Attallah, Nizar
author_facet Gupta, Sudeendra
Madhyastha, Rakesh
Hamed, Fadi
Balkis, Maher
El Nekidy, Wasim
Attallah, Nizar
author_sort Gupta, Sudeendra
collection PubMed
description Novel coronavirus disease 2019 (COVID-19) is a highly infectious, rapidly spreading viral disease. As of writing this article, there are over 4.4 million people affected by COVID-19, and unfortunately, 300,000 have succumbed to the infection. In this article, we address a particularly more susceptible group of the population of end-stage renal disease (ESRD) patients on dialysis who may potentially benefit from being treated with tocilizumab. The use of tocilizumab has not been reported widely in ESRD patients on dialysis to treat COVID-19. In this case report, we describe a patient with ESRD on hemodialysis who was admitted to the intensive care unit, with severe pneumonia secondary to COVID-19 infection. This patient was treated with tocilizumab 400 mg intravenous and had a favorable outcome with no apparent adverse events.
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spelling pubmed-76824752020-12-08 Tocilizumab Use in a Chronic Hemodialysis Patient for the Management of COVID-19-Associated Pneumonia and Acute Respiratory Distress Syndrome Gupta, Sudeendra Madhyastha, Rakesh Hamed, Fadi Balkis, Maher El Nekidy, Wasim Attallah, Nizar Case Rep Nephrol Case Report Novel coronavirus disease 2019 (COVID-19) is a highly infectious, rapidly spreading viral disease. As of writing this article, there are over 4.4 million people affected by COVID-19, and unfortunately, 300,000 have succumbed to the infection. In this article, we address a particularly more susceptible group of the population of end-stage renal disease (ESRD) patients on dialysis who may potentially benefit from being treated with tocilizumab. The use of tocilizumab has not been reported widely in ESRD patients on dialysis to treat COVID-19. In this case report, we describe a patient with ESRD on hemodialysis who was admitted to the intensive care unit, with severe pneumonia secondary to COVID-19 infection. This patient was treated with tocilizumab 400 mg intravenous and had a favorable outcome with no apparent adverse events. Hindawi 2020-11-23 /pmc/articles/PMC7682475/ /pubmed/33299621 http://dx.doi.org/10.1155/2020/8829309 Text en Copyright © 2020 Sudeendra Gupta et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Gupta, Sudeendra
Madhyastha, Rakesh
Hamed, Fadi
Balkis, Maher
El Nekidy, Wasim
Attallah, Nizar
Tocilizumab Use in a Chronic Hemodialysis Patient for the Management of COVID-19-Associated Pneumonia and Acute Respiratory Distress Syndrome
title Tocilizumab Use in a Chronic Hemodialysis Patient for the Management of COVID-19-Associated Pneumonia and Acute Respiratory Distress Syndrome
title_full Tocilizumab Use in a Chronic Hemodialysis Patient for the Management of COVID-19-Associated Pneumonia and Acute Respiratory Distress Syndrome
title_fullStr Tocilizumab Use in a Chronic Hemodialysis Patient for the Management of COVID-19-Associated Pneumonia and Acute Respiratory Distress Syndrome
title_full_unstemmed Tocilizumab Use in a Chronic Hemodialysis Patient for the Management of COVID-19-Associated Pneumonia and Acute Respiratory Distress Syndrome
title_short Tocilizumab Use in a Chronic Hemodialysis Patient for the Management of COVID-19-Associated Pneumonia and Acute Respiratory Distress Syndrome
title_sort tocilizumab use in a chronic hemodialysis patient for the management of covid-19-associated pneumonia and acute respiratory distress syndrome
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682475/
https://www.ncbi.nlm.nih.gov/pubmed/33299621
http://dx.doi.org/10.1155/2020/8829309
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