Cargando…
A global analysis of low-complexity regions in the Trypanosoma brucei proteome reveals enrichment in the C-terminus of nucleic acid binding proteins providing potential targets of phosphorylation
Background: Low-complexity regions (LCRs) on proteins have attracted increasing attention recently due to their role in the assembly of membraneless organelles or granules by liquid-liquid phase separation. Several examples of such granules have been shown to sequester RNA and proteins in an inactiv...
Autores principales: | Cayla, Mathieu, Matthews, Keith R., Ivens, Alasdair C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682498/ https://www.ncbi.nlm.nih.gov/pubmed/33274300 http://dx.doi.org/10.12688/wellcomeopenres.16286.2 |
Ejemplares similares
-
Genome-wide RNAi selection identifies a regulator of transmission stage-enriched gene families and cell-type differentiation in Trypanosoma brucei
por: Rico, Eva, et al.
Publicado: (2017) -
A gene expression comparison of Trypanosoma brucei and Trypanosoma congolense in the bloodstream of the mammalian host reveals species-specific adaptations to density-dependent development
por: Silvester, Eleanor, et al.
Publicado: (2018) -
Basement membrane proteins as a substrate for efficient Trypanosoma brucei differentiation in vitro
por: Rojas, Federico, et al.
Publicado: (2021) -
Developmental competence and antigen switch frequency can be uncoupled in Trypanosoma brucei
por: McWilliam, Kirsty R., et al.
Publicado: (2019) -
High-Throughput Chemical Screening for Antivirulence Developmental Phenotypes in Trypanosoma brucei
por: MacGregor, Paula, et al.
Publicado: (2014)