CXCL-8-dependent and -independent neutrophil activation in COPD: experiences from a pilot study of the CXCR2 antagonist danirixin

The implications of these findings are significant for development of CXCR2 antagonists and other mechanisms targeting neutrophil activation or NETosis, suggesting that IL-8-dependent mechanisms will only work in a subset of COPD patients https://bit.ly/32SeisO

Detalles Bibliográficos
Autores principales: Keir, Holly R., Richardson, Hollian, Fillmore, Christina, Shoemark, Amelia, Lazaar, Aili L., Miller, Bruce E., Tal-Singer, Ruth, Chalmers, James D., Mohan, Divya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2020
Materias:
Original Research Letters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682717/
https://www.ncbi.nlm.nih.gov/pubmed/33263062
http://dx.doi.org/10.1183/23120541.00583-2020

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