Cargando…

Association of Hypertension and Blood Pressure With Kidney Cancer Risk: A Nationwide Population-Based Cohort Study

Data regarding health behavior-related factors and systolic or diastolic blood pressure to evaluate the association between blood pressure and kidney cancer are lacking. Using nationally representative data from the Korean National Health Insurance System, 9 746 445 participants without kidney cance...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Chang Seong, Han, Kyung-Do, Choi, Hong Sang, Bae, Eun Hui, Ma, Seong Kwon, Kim, Soo Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott, Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682799/
https://www.ncbi.nlm.nih.gov/pubmed/32336229
http://dx.doi.org/10.1161/HYPERTENSIONAHA.120.14820
_version_ 1783612750595883008
author Kim, Chang Seong
Han, Kyung-Do
Choi, Hong Sang
Bae, Eun Hui
Ma, Seong Kwon
Kim, Soo Wan
author_facet Kim, Chang Seong
Han, Kyung-Do
Choi, Hong Sang
Bae, Eun Hui
Ma, Seong Kwon
Kim, Soo Wan
author_sort Kim, Chang Seong
collection PubMed
description Data regarding health behavior-related factors and systolic or diastolic blood pressure to evaluate the association between blood pressure and kidney cancer are lacking. Using nationally representative data from the Korean National Health Insurance System, 9 746 445 participants without kidney cancer between January 1, 2006 and December 31, 2009 were followed up until December 31, 2017 to obtain data regarding cancer incidence. Participants were categorized, according to blood pressure, as normal (<120/80 mm Hg), elevated (120–129/<80 mm Hg), and hypertensive (≥130/80 mm Hg) with or without antihypertensive medication, according to the 2017 American College of Cardiology and American Heart Association blood pressure guidelines. Kidney cancer was noted in 11 083 participants during the 8-year follow-up. Participants with hypertension were at higher risk for kidney cancer than those without hypertension. Participants with hypertension using medication had a higher cancer risk than those not using medication and those with elevated blood pressure. The risk of kidney cancer significantly increased with higher systolic or diastolic blood pressure, in a dose-dependent manner, even after adjusting for antihypertensive medication use. Therefore, hypertension and high systolic or diastolic blood pressure, compared with normal blood pressure, were associated with an increased risk of kidney cancer.
format Online
Article
Text
id pubmed-7682799
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Lippincott, Williams & Wilkins
record_format MEDLINE/PubMed
spelling pubmed-76827992020-12-01 Association of Hypertension and Blood Pressure With Kidney Cancer Risk: A Nationwide Population-Based Cohort Study Kim, Chang Seong Han, Kyung-Do Choi, Hong Sang Bae, Eun Hui Ma, Seong Kwon Kim, Soo Wan Hypertension Original Articles Data regarding health behavior-related factors and systolic or diastolic blood pressure to evaluate the association between blood pressure and kidney cancer are lacking. Using nationally representative data from the Korean National Health Insurance System, 9 746 445 participants without kidney cancer between January 1, 2006 and December 31, 2009 were followed up until December 31, 2017 to obtain data regarding cancer incidence. Participants were categorized, according to blood pressure, as normal (<120/80 mm Hg), elevated (120–129/<80 mm Hg), and hypertensive (≥130/80 mm Hg) with or without antihypertensive medication, according to the 2017 American College of Cardiology and American Heart Association blood pressure guidelines. Kidney cancer was noted in 11 083 participants during the 8-year follow-up. Participants with hypertension were at higher risk for kidney cancer than those without hypertension. Participants with hypertension using medication had a higher cancer risk than those not using medication and those with elevated blood pressure. The risk of kidney cancer significantly increased with higher systolic or diastolic blood pressure, in a dose-dependent manner, even after adjusting for antihypertensive medication use. Therefore, hypertension and high systolic or diastolic blood pressure, compared with normal blood pressure, were associated with an increased risk of kidney cancer. Lippincott, Williams & Wilkins 2020-06 2020-04-27 /pmc/articles/PMC7682799/ /pubmed/32336229 http://dx.doi.org/10.1161/HYPERTENSIONAHA.120.14820 Text en © 2020 The Authors. Hypertension is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution Non-Commercial-NoDerivs (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited, the use is noncommercial, and no modifications or adaptations are made.
spellingShingle Original Articles
Kim, Chang Seong
Han, Kyung-Do
Choi, Hong Sang
Bae, Eun Hui
Ma, Seong Kwon
Kim, Soo Wan
Association of Hypertension and Blood Pressure With Kidney Cancer Risk: A Nationwide Population-Based Cohort Study
title Association of Hypertension and Blood Pressure With Kidney Cancer Risk: A Nationwide Population-Based Cohort Study
title_full Association of Hypertension and Blood Pressure With Kidney Cancer Risk: A Nationwide Population-Based Cohort Study
title_fullStr Association of Hypertension and Blood Pressure With Kidney Cancer Risk: A Nationwide Population-Based Cohort Study
title_full_unstemmed Association of Hypertension and Blood Pressure With Kidney Cancer Risk: A Nationwide Population-Based Cohort Study
title_short Association of Hypertension and Blood Pressure With Kidney Cancer Risk: A Nationwide Population-Based Cohort Study
title_sort association of hypertension and blood pressure with kidney cancer risk: a nationwide population-based cohort study
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682799/
https://www.ncbi.nlm.nih.gov/pubmed/32336229
http://dx.doi.org/10.1161/HYPERTENSIONAHA.120.14820
work_keys_str_mv AT kimchangseong associationofhypertensionandbloodpressurewithkidneycancerriskanationwidepopulationbasedcohortstudy
AT hankyungdo associationofhypertensionandbloodpressurewithkidneycancerriskanationwidepopulationbasedcohortstudy
AT choihongsang associationofhypertensionandbloodpressurewithkidneycancerriskanationwidepopulationbasedcohortstudy
AT baeeunhui associationofhypertensionandbloodpressurewithkidneycancerriskanationwidepopulationbasedcohortstudy
AT maseongkwon associationofhypertensionandbloodpressurewithkidneycancerriskanationwidepopulationbasedcohortstudy
AT kimsoowan associationofhypertensionandbloodpressurewithkidneycancerriskanationwidepopulationbasedcohortstudy