Hypomethylation of GDNF family receptor alpha 1 promotes epithelial-mesenchymal transition and predicts metastasis of colorectal cancer

Tumor metastasis is the major cause of poor prognosis and mortality in colorectal cancer (CRC). However, early diagnosis of highly metastatic CRC is currently difficult. In the present study, we screened for a novel biomarker, GDNF family receptor alpha 1 (GFRA1) based on the expression and methylat...

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Detalles Bibliográficos
Autores principales: Dong, Zhexu, Dai, Lei, Zhang, Yong, Fang, Chao, Shi, Gang, Chen, Ye, Li, Junshu, Wang, Qin, Fu, Jiamei, Yu, Yan, Wang, Wenshuang, Cheng, Lin, Liu, Yi, Lin, Yi, Wang, Yuan, Wang, Qingnan, Wang, Huiling, Zhang, Hantao, Zhang, Yujing, Su, Xiaolan, Zhang, Shuang, Wang, Feng, Qiu, Meng, Zhou, Zongguang, Deng, Hongxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682896/
https://www.ncbi.nlm.nih.gov/pubmed/33175846
http://dx.doi.org/10.1371/journal.pgen.1009159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682896/
https://www.ncbi.nlm.nih.gov/pubmed/33175846
http://dx.doi.org/10.1371/journal.pgen.1009159

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