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Nutrition, the digestive system and immunity in COVID-19 infection

The current review aimed to synthesize the literature on the complex relationship between food consumption and nutritional status as well as the digestive system in order to examine the relationship between immunity and potential responses to COVID-19 infection. The goal is to help inform the many h...

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Autores principales: Bold, Justine, Harris, Miranda, Fellows, Lindsey, Chouchane, Manal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682975/
https://www.ncbi.nlm.nih.gov/pubmed/33244375
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author Bold, Justine
Harris, Miranda
Fellows, Lindsey
Chouchane, Manal
author_facet Bold, Justine
Harris, Miranda
Fellows, Lindsey
Chouchane, Manal
author_sort Bold, Justine
collection PubMed
description The current review aimed to synthesize the literature on the complex relationship between food consumption and nutritional status as well as the digestive system in order to examine the relationship between immunity and potential responses to COVID-19 infection. The goal is to help inform the many healthcare professionals working with COVID-19 patients. A literature search was performed on PubMed, Scopus, and EMBASE databases. Hand searches were also undertaken using Google and reference lists to identify recent evidence. Studies were critically appraised, and the findings were analyzed by narrative synthesis. Nutritional status can impact immunity in several ways, including affecting susceptibility to infection, severity of disease, and recovery time, and is therefore a significant consideration in the management of COVID-19. COVID-19 can also impact digestive function, which can further impact nutritional status. The role of Vitamin D deficiency in vulnerability to severe respiratory infections, including COVID-19, has been recognized, and it may have a role in treatment where deficiency is indicated. Healthcare professionals should be aware that obesity may be accompanied by micronutrient malnutrition including vitamin D deficiency and alterations in the microbiome and inflammatory responses, which can further impact immunity and disease severity. Multidisciplinary team-work is recommended in the management of patients with COVID-19, and approaches should include a consideration of nutritional status (both macronutrients and micronutrients), body weight, and gastrointestinal signs and symptom.
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spelling pubmed-76829752020-11-25 Nutrition, the digestive system and immunity in COVID-19 infection Bold, Justine Harris, Miranda Fellows, Lindsey Chouchane, Manal Gastroenterol Hepatol Bed Bench Review Article The current review aimed to synthesize the literature on the complex relationship between food consumption and nutritional status as well as the digestive system in order to examine the relationship between immunity and potential responses to COVID-19 infection. The goal is to help inform the many healthcare professionals working with COVID-19 patients. A literature search was performed on PubMed, Scopus, and EMBASE databases. Hand searches were also undertaken using Google and reference lists to identify recent evidence. Studies were critically appraised, and the findings were analyzed by narrative synthesis. Nutritional status can impact immunity in several ways, including affecting susceptibility to infection, severity of disease, and recovery time, and is therefore a significant consideration in the management of COVID-19. COVID-19 can also impact digestive function, which can further impact nutritional status. The role of Vitamin D deficiency in vulnerability to severe respiratory infections, including COVID-19, has been recognized, and it may have a role in treatment where deficiency is indicated. Healthcare professionals should be aware that obesity may be accompanied by micronutrient malnutrition including vitamin D deficiency and alterations in the microbiome and inflammatory responses, which can further impact immunity and disease severity. Multidisciplinary team-work is recommended in the management of patients with COVID-19, and approaches should include a consideration of nutritional status (both macronutrients and micronutrients), body weight, and gastrointestinal signs and symptom. Shaheed Beheshti University of Medical Sciences 2020 /pmc/articles/PMC7682975/ /pubmed/33244375 Text en ©2020 RIGLD, Research Institute for Gastroenterology and Liver Diseases This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Bold, Justine
Harris, Miranda
Fellows, Lindsey
Chouchane, Manal
Nutrition, the digestive system and immunity in COVID-19 infection
title Nutrition, the digestive system and immunity in COVID-19 infection
title_full Nutrition, the digestive system and immunity in COVID-19 infection
title_fullStr Nutrition, the digestive system and immunity in COVID-19 infection
title_full_unstemmed Nutrition, the digestive system and immunity in COVID-19 infection
title_short Nutrition, the digestive system and immunity in COVID-19 infection
title_sort nutrition, the digestive system and immunity in covid-19 infection
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682975/
https://www.ncbi.nlm.nih.gov/pubmed/33244375
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