Talin-activated vinculin interacts with branched actin networks to initiate bundles

Vinculin plays a fundamental role in integrin-mediated cell adhesion. Activated by talin, it interacts with diverse adhesome components, enabling mechanical coupling between the actin cytoskeleton and the extracellular matrix. Here we studied the interactions of activated full-length vinculin with a...

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Detalles Bibliográficos
Autores principales: Boujemaa-Paterski, Rajaa, Martins, Bruno, Eibauer, Matthias, Beales, Charlie T, Geiger, Benjamin, Medalia, Ohad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682986/
https://www.ncbi.nlm.nih.gov/pubmed/33185186
http://dx.doi.org/10.7554/eLife.53990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682986/
https://www.ncbi.nlm.nih.gov/pubmed/33185186
http://dx.doi.org/10.7554/eLife.53990

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