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The deubiquitylase Ubp15 couples transcription to mRNA export

Nuclear export of messenger RNAs (mRNAs) is intimately coupled to their synthesis. pre-mRNAs assemble into dynamic ribonucleoparticles as they are being transcribed, processed, and exported. The role of ubiquitylation in this process is increasingly recognized but, while a few E3 ligases have been s...

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Detalles Bibliográficos
Autores principales: Eyboulet, Fanny, Jeronimo, Célia, Côté, Jacques, Robert, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682988/
https://www.ncbi.nlm.nih.gov/pubmed/33226341
http://dx.doi.org/10.7554/eLife.61264