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Generation of liver bipotential organoids with a small-molecule cocktail

Understanding the mechanism of how cholangiocytes (liver ductal cells) are activated upon liver injury and specified to hepatocytes would permit liver regenerative medicine. Here we achieved long-term in vitro expansion of mouse liver organoids by modulating signaling pathways with a combination of...

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Detalles Bibliográficos
Autores principales:	Wang, Xin, Ni, Chao, Jiang, Ning, Wei, Jinsong, Liang, Jianqing, Zhao, Bing, Lin, Xinhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683013/ https://www.ncbi.nlm.nih.gov/pubmed/32232340 http://dx.doi.org/10.1093/jmcb/mjaa010

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